J Korean Neuropsychiatr Assoc.  1998 May;37(3):509-514.

Preliminary MRI Study of Cavum Septi Pellucidi in Schizophrenia

• Kim CE
• Shin SE
• Kang MH
• Lim MK

Abstract

OBJECTIVES
To test the neurodevelopmental hypothesis of the schizophrenia, we compared MR brain scans of schizophrenic patients with headache patients. METHOD: We conducted 7mm-slice magnetic resonance imaging study to evaluate the prevalence of CSF in a sample of 28 headache patients and 23 schizophrenic patients. All subjects are right-handed person by Annett's questionaires.
RESULTS
Any size CSF was fecund 13/23(56.5%)schizophrenics and 16/28(57.1%) of headache patients. But larger CSF was found 26.1% of schizophrenics and 10.7% of headache patients. No statistically significant difference in gender and clinical subtype.
CONCLUSIONS
Higher incidence of CSF in schizophrenic patients supports the hypothesis that anomalous development of the brain is an important aspect of the schizophrenia.

Keyword

Schizophrenia; CSP; Neurodevelopmental; Hypothesis; MRI

MeSH Terms

Brain
Headache
Humans
Incidence
Magnetic Resonance Imaging*
Prevalence
Schizophrenia*