J Korean Ophthalmol Soc.  2007 Feb;48(2):328-331.

Acanthamoeba Keratitis Related to Orthokeratology Contact Lens

Affiliations
  • 1The Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea. ongsool@pusan.ac.kr
  • 2Apgujung St. Mary's Eye Center, Seoul, Korea.
  • 3The Department of Parasitology, College of Medicine, Pusan National University, Pusan, Korea.

Abstract

PURPOSE: To report 4 cases of Acanthamoeba keratitis related to orthokeratology lens overnight wear.
METHODS
Four patients had histories of overnight orthkeratology lens wear of 10 months to 3 years when they presented with corneal ulcers.
RESULTS
The organism isolated by corneal scraping was Aanthamoeba. The patients were treated with polyhexamethylene biguanide (PHMB), and chlorhexidine, resulting in a resolution of ocular inflammation.
CONCLUSION
The risk of Acanthamoeba keratitis as a potential complication of overnight orthkeratology should be considered.

Keyword

Acanthamoeba keratitis; Chlorhexidine; Orthokeratology; Polyhexamethylene biguanide (PHMB)

MeSH Terms

Acanthamoeba Keratitis*
Acanthamoeba*
Chlorhexidine
Humans
Inflammation
Ulcer
Chlorhexidine
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