J Korean Ophthalmol Soc.  2006 Jun;47(6):986-990.

A Case of Granulocytic Sarcoma Involving the Forniceal Conjunctiva

• Lee HS
• Park JW
• Yang SW

Abstract

PURPOSE: We report a case of the granulocytic sarcoma located at the conjunctival fornix in a 10-year-old girl with acute myeloid leukemia, who was in complete remission after bone marrow transplantation.
METHODS
A 10-year-old girl had a 1-week history of firm, dark brown conjunctival mass at lower fornix and mild lid swelling of the right eye. Several months previously she had had some chalazions at lower lid and a history of acute myeloid leukemia that was currently in complete remission after bone marrow transplantation. Other ocular manifestations were not specific. Excision of the conjunctival mass and a biopsy for diagnostic and therapeutic purposes were performed.
RESULTS
The 12 x 6 x 5 mm-sized mass was totally excised. The pathologic examination was consistent with granulocytic sarcoma. Three weeks after the biopsy, the patient had a relapse of acute myeloid leukemia. She died 2 months later while undergoing intensive therapy.
CONCLUSIONS
This condition should be considered in the diagnosis of granulocytic sarcoma in patients with a history of acute myeloid leukemia.

Keyword

Acute myeloid leukemia; Chalazion; Conjunctival mass; Granulocytic sarcoma

MeSH Terms

Biopsy
Bone Marrow Transplantation
Chalazion
Child
Conjunctiva*
Diagnosis
Female
Humans
Leukemia, Myeloid, Acute
Recurrence
Sarcoma, Myeloid*