- Changing the strategic paradigm for the treatment of adult acute myeloid leukemia
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Cheong JW, Min YH
- KMID: 2541904
- J Korean Med Assoc.
- 2023 Apr;66(4):234-244.
- doi: 10.5124/jkma.2023.66.4.234
Background: Acute myeloid leukemia (AML) is a representative blood cancer, accounting for most adult leukemia cases in Korea. Until recently, intensive chemotherapy and hematopoietic stem cell transplantation were the only... -
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- The impact of COVID-19 on acute myeloid leukemia patients undergoing allogeneic stem cell transplantation: a concise review
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Mansour RO, El-Ashwah S, Denewer M
- KMID: 2541060
- Blood Res.
- 2023 Mar;58(1):13-19.
- doi: 10.5045/br.2023.2022144
This study aimed to delineate the possible impact of COVID-19 on acute myeloid leukemia (AML) patients in terms of diagnosis, chemotherapy, bone marrow transplant, and vaccination response. Allogeneic stem cell... -
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- Clinical Experience of Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients Aged 60 Years and Older in South Korea
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Ji YS, Ahn JS, Yun J, Jang GH, Lim SH, Kim SH, Kim CK, Won JH, Park SK
- KMID: 2538962
- Yonsei Med J.
- 2023 Feb;64(2):123-132.
- doi: 10.3349/ymj.2022.0331
Purpose: The purpose of this study is to share our outcomes and experiences on allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients aged 60 years and older with myelodysplastic... -
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- Diagnostic Approach for Acute Myeloid Leukemia Based on the World Health Organization Classification of Hematologic Neoplasms
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Cho YU
- KMID: 2534385
- Korean J Med.
- 2022 Oct;97(5):308-318.
- doi: 10.3904/kjm.2022.97.5.308
Acute myeloid leukemias (AMLs) are heterogeneous hematologic neoplasms characterized by myeloblast or promyelocyte proliferation without normal differentiation. The World Health Organization (WHO) classifies AMLs on the basis of chromosomal and... -
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- Outcome of Intensive Therapy for Children with Relapsed Acute Myeloid Leukemia: A Single Institution Korean Study
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Lee JW, Yoo JW, Kim S, Jang PS, Chung NG, Cho B
- KMID: 2534202
- Cancer Res Treat.
- 2022 Oct;54(4):1230-1239.
- doi: 10.4143/crt.2021.1011
Purpose Approximately 30%-40% of pediatric acute myeloid leukemia (AML) patients relapse. In this study, we analyzed the outcome and prognostic factors of relapsed AML patients who had previously received first-line... -
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- A Novel Germline Mutation in DDX41 Predisposed to Myelodysplasia/Acute Myeloid Leukemia
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Kwak MS, Jeong IH, Kim SH, Kim N
- KMID: 2538608
- Lab Med Online.
- 2022 Jul;12(3):209-213.
- doi: 10.47429/lmo.2022.12.3.209
Germline DDX41lesions indicate a hereditary myelodysplastic syndrome and acute myeloid leukemia (MDS/AML). Canonical somatic mutations in this gene often coincide as a second hit with germline DDX41mutations. We report a... -
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- Large Vessel Vasculitis as an Initial Manifestation of Acute Myeloid Leukemia: A Case Report
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Jeon G, Yang D, Jang J, Kang J
- KMID: 2532183
- J Korean Soc Radiol.
- 2022 Jul;83(4):918-923.
- doi: 10.3348/jksr.2021.0114
Large vessel vasculitis is characterized by chronic inflammation within the aortic wall and its major branches. The inflammation is considered to occur as a result of immune dysregulation. Hematologic malignancy... -
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- Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
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Kwon CI, Lee GW, Kim CY
- KMID: 2530023
- Ann Dermatol.
- 2022 Jun;34(3):212-215.
- doi: 10.5021/ad.2022.34.3.212
Unlike classic pyoderma gangrenosum (PG), the bullous variant of PG is typically represented by a painful erythematous papule, plaque, and superficial bulla that progress into the ulceration with bullous margin.... -
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- Human acute myeloid leukemia stem cells: evolution of concept
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Shin DY
- KMID: 2529310
- Blood Res.
- 2022 Apr;57(S1):S67-S74.
- doi: 10.5045/br.2022.2021221
The history of human acute myeloid leukemia stem cells (AMLSCs) began in a seminal study performed by Lapidot and Dick, proving that only CD34+CD38- human primary acute myeloid leukemia (AML)... -
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- FLT3 mutations in acute myeloid leukemia: a review focusing on clinically applicable drugs
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Ahn JS, Kim HJ
- KMID: 2529304
- Blood Res.
- 2022 Apr;57(S1):S32-S36.
- doi: 10.5045/br.2022.2022017
FMS-like tyrosine kinase 3 (FLT3) mutations, the most frequently detected genetic aberrations in patients with acute myeloid leukemia (AML), are identified in approximately 30% of patients with newly diagnosed AML... -
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- Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea
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Choi YB, Yoo KH
- KMID: 2528226
- Cancer Res Treat.
- 2022 Apr;54(2):572-578.
- doi: 10.4143/crt.2021.368
Purpose Children with Down syndrome (DS) show a higher risk of acute leukemia than those without DS. In this study, we investigated the nationwide incidence of acute leukemia among children with... -
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- A Case of Myeloid Sarcoma Preceding the Diagnosis of Acute Myeloid Leukemia
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Lee YY, Yim SH, Hong D, Jung KE, Lee Y, Seo YJ, Park SH
- KMID: 2527688
- Korean J Dermatol.
- 2022 Mar;60(3):197-199.
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- A Case of Erythema Nodosum Associated with Relapse in Acute Myeloid Leukemia
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Yun J, Bae KN, Son JH, Kim H, Ko H, Kim B, Kim MB, Shin K
- KMID: 2527684
- Korean J Dermatol.
- 2022 Mar;60(3):190-191.
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- IDH1/2 mutations in acute myeloid leukemia
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Byun JM, Yoo SJ, Kim HJ, Ahn JS, Koh Y, Jang JH, Yoon SS
- KMID: 2527492
- Blood Res.
- 2022 Mar;57(1):13-19.
- doi: 10.5045/br.2021.2021152
The mutational and epigenetic landscape of acute myeloid leukemia (AML) has become increasingly well understood in recent years, informing on biological targets for precision medicine. Among the most notable findings... -
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- JAK2V617F-Positive Acute Myeloid Leukemia: Clinicopathological Features of Two Cases
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Lee Y, Lee JY, Lee JO, Bang SM, Hwang SM
- KMID: 2538584
- Lab Med Online.
- 2022 Jan;12(1):53-57.
- doi: 10.47429/lmo.2022.12.1.53
Although the JAK2V617F mutation is a common genetic basis for the BCR-ABL1-negative myeloproliferative neoplasm (MPN), it is very rarely observed in acute myeloid leukemia (AML) without antecedent MPN. While JAK2V617F... -
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- Venetoclax with Azacitidine Induced Tumor Lysis Syndrome in an Elderly Patient with Acute Myeloid Leukemia: A Case Report
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Kim M, Bang HJ, Song GY, Ahn SY, Jung SH, Song YS, Ahn JS
- KMID: 2525853
- Electrolyte Blood Press.
- 2021 Dec;19(2):46-50.
- doi: 10.5049/EBP.2021.19.2.46
Combination treatment with hypomethylating agents (HMAs) and venetoclax is being used increasingly in elderly patients with acute myeloid leukemia (AML). Venetoclax with HMAs has been reported to be associated with tumor... -
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- Therapy-Related Acute Myeloid Leukemia Diagnosed at Postmortem in a Long-term Survivor of Advanced Hepatocellular Carcinoma
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Lee KR, Paik JH, Lee SD, Kim MY
- KMID: 2526234
- Korean J Leg Med.
- 2021 Nov;45(4):139-144.
- doi: 10.7580/kjlm.2021.45.4.139
Acute myeloid leukemia (AML) is a common hematologic malignancy with high mortality and a short survival period in adults. About 10% of these cases, called therapy-related AML, are reported to... -
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- Phospholipase C Beta 2 Protein Overexpression Is a Favorable Prognostic Indicator in Newly Diagnosed Normal Karyotype Acute Myeloid Leukemia
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Park MS, Lee YE, Kim HR, Shin JH, Cho HW, Lee JH, Shin MG
- KMID: 2512721
- Ann Lab Med.
- 2021 Jul;41(4):409-413.
- doi: 10.3343/alm.2021.41.4.409
Phospholipase C beta 2 (PLC-β2) regulates various essential functions in cell signaling, differentiation, growth, and mobility. We investigated the clinical implications of PLC-β2 protein expression in newly diagnosed normal karyotype... -
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- Transfusion Dependency in Patients with Acute Myeloid Leukemia during Induction Chemotherapy
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Park HS, Shin KS, Son BR
- KMID: 2515263
- Korean J Blood Transfus.
- 2021 Apr;32(1):35-42.
- doi: 10.17945/kjbt.2021.32.1.3 5
Background: Blood transfusion is frequently performed as a supportive therapy during the diagnosis and chemotherapy of acute myeloid leukemia (AML). This study examined the frequency of blood transfusion and analyzed... -
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- First Case Report of Acute Myeloid Leukemia with MN1-ETV6 Rearrangement at Relapse
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Lee JJ, Cho HE, Park KS, Kim YJ, Cho SY, Han JJ, Lee WI, Park TS
- KMID: 2525807
- Lab Med Online.
- 2021 Apr;11(2):145-148.
- doi: 10.47429/lmo.2021.11.2.145
MN1-ETV6 rearrangement is rarely detected in patients with myeloid neoplasms, such as acute myeloid leukemia, myelodysplastic syndrome, and myelodysplastic/myeloproliferative neoplasms. Usually, MN1-ETV6 rearrangement is found at diagnosis. Here, we report... -
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