J Korean Acad Rehabil Med.  2010 Feb;34(1):96-98.

Bilateral Hypertrophic Olivary Degeneration with Oculopalatal Tremor after Brainstem Hemorrhage: A case report

• Lee GH
• Kim SJ
• Yoon JS
• Jo JM

Abstract

Hypertrophic olivary degeneration is a form of transynaptic degeneration, which is caused by a lesion in the dentate-rubro-olivary pathway. Commonly described lesions were brainstem stroke, neoplasm, demyelination, and trauma. It's clinical presentations are Holmes tremor, and palatal tremor. This case was a 49-year-old man who was diagnosed as bilateral brainstem hemorrhage. About 2 months later, he had developed bilateral Holmes tremor of upper extremities and oculopalatal termor. Brain MRI was performed at 13 months after onset. MRI showed hyperintense and hypertrophied lesion on T2-weighted image in both inferior olivary nuclei.

Keyword

Hypertrophic olivary degeneration; Oculopalatal tremor

MeSH Terms

Brain
Brain Stem
Brain Stem Infarctions
Demyelinating Diseases
Hemorrhage
Humans
Middle Aged
Tremor
Upper Extremity