J Korean Surg Soc.  2013 Jan;84(1):1-8.

Surgical issues in locally advanced rectal cancer treated by preoperative chemoradiotherapy

Affiliations
  • 1Department of Surgery, Asan Medical Center, Institute of Innovative Cancer Research, University of Ulsan College of Medicine, Seoul, Korea. jckim@amc.seoul.kr

Abstract

The standard treatment for patients with locally advanced rectal cancer is preoperative chemoradiotherapy followed by total mesorectal excision. This approach is supported by randomized trials, but there are still many unanswered questions about the multimodal management of rectal cancer. In surgical terms, these include the optimal time interval between completion of chemoradiotherapy and surgery; adequate distal resection margin and circumferential radial margin; sphincter preservation; laparoscopic surgery; and conservative management, including a 'wait and see' policy and local excision. This review considers these controversial issues in preoperative chemoradiotherapy.

Keyword

Rectal cancer; Chemoradiotherapy; Surgical procedures

MeSH Terms

Chemoradiotherapy
Humans
Rectal Neoplasms
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