- Neoadjuvant chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: Meta-analysis and trial sequential analysis of randomized controlled trials
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Hajibandeh S, Hajibandeh S, Intrator C, Hassan K, Sehmbhi M, Shah J, Mazumdar E, Kausar A, Satyadas T
- KMID: 2539511
- Ann Hepatobiliary Pancreat Surg.
- 2023 Feb;27(1):28-39.
- doi: 10.14701/ahbps.22-052
We aimed to compare resection and survival outcomes of neoadjuvant chemoradiotherapy (CRT) and immediate surgery in patients with resectable pancreatic cancer (RPC) or borderline resectable pancreatic cancer (BRPC). In compliance... -
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- An investigation into tumor regression grade as a parameter for locally advanced rectal cancer and 5-year overall survival rate
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Laohawiriyakamol S, Chaochankit W, Wanichsuwan W, Kanjanapradit K, Laohawiriyakamol T
- KMID: 2539716
- Ann Coloproctol.
- 2023 Feb;39(1):59-70.
- doi: 10.3393/ac.2021.01011.0144
Purpose: The standard treatment for locally advanced rectal cancer (LARC) is neoadjuvant chemoradiation (nCRT) followed by surgery. Several parameters are associated with patient survival in LARC. One of these parameters... -
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- Benefits of Adjuvant Chemotherapy for Clinical T3-4N0 Rectal Cancer After Preoperative Chemoradiotherapy
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Bang HJ, Shim HJ, Hwang JE, Bae WK, Chung IJ, Cho SH
- KMID: 2538699
- Chonnam Med J.
- 2023 Jan;59(1):76-82.
- doi: 10.4068/cmj.2023.59.1.76
While the guidelines for adjuvant chemotherapy (AC) for colon cancer are relatively standardized, those for early rectal cancer are still lacking. We therefore evaluated the role of AC in clinical... -
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- A Phase II Study of Preoperative Chemoradiotherapy with Capecitabine Plus Simvastatin in Patients with Locally Advanced Rectal Cancer
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Jo H, Kim ST, Lee J, Park SH, Park JO, Park YS, Lim HY, Yu JI, Park HC, Choi DH, Park Y, Cho YB, Huh JW, Yun SH, Kim HC, Lee WY, Kang WK
- KMID: 2538004
- Cancer Res Treat.
- 2023 Jan;55(1):189-195.
- doi: 10.4143/crt.2021.1527
Purpose The purpose of this phase II trial was to evaluate whether the addition of simvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, to preoperative chemoradiotherapy (CRT) with capecitabine confers... -
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- Role of Post-Treatment 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients Receiving Definitive Chemoradiation for Locally Advanced Head and Neck Squamous Cell Carcinomas
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Kim JJ, Oh SB, Jung KS, Park K, Kim SJ, Ki Y, Lee JC, Oh SY
- KMID: 2536185
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2022 Nov;65(11):697-704.
- doi: 10.3342/kjorl-hns.2022.00626
Background and Objectives 18F-fluorodeoxyglucose PET/CT scans can be a useful method to detect recurrence. However, its role in locally advanced head and neck squamous cell carcinomas (HNSCCs) patients after definitive... -
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- Clinical Features and Prognosis of Diffuse Midline Glioma: A Series of 24 Cases
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Jang SW, Song SW, Kim YH, Cho YH, Hong SH, Kim JH, Ra YS, Chong S
- KMID: 2534724
- Brain Tumor Res Treat.
- 2022 Oct;10(4):255-264.
- doi: 10.14791/btrt.2022.0035
Background Diffuse midline glioma (DMG) which occurs in midline structures and characterized by harboring K27M mutation in genes encoding the histone 3 protein is classified as World Health Organization (WHO)... -
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- Role of Esophagectomy after Chemoradiation Therapy in Patients with Locally Advanced Squamous Cell Carcinoma: A Comparative Analysis Stratified by Clinical Response to Chemoradiation Therapy
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Yu J, Kim JH, Kim SB, Park SR, Kim YH, Kim HR, Lee HJ, Song HJ, Song KJ, Jang JY, Jo YY, Yoo YJ
- KMID: 2534194
- Cancer Res Treat.
- 2022 Oct;54(4):1148-1156.
- doi: 10.4143/crt.2021.885
Purpose This study aimed to evaluate the long-term effect of esophagectomy in patients with esophageal squamous cell carcinoma (ESCC) by comparing the chemoradiotherapy (CRT)-only group and the trimodality treatment (TMT) group... -
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- Association between microsatellite instability and tumor response to neoadjuvant chemoradiotherapy for rectal cancer
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Lee SY, Kim DW, Lee J, Park Hm, Kim CH, Lee KH, Oh HK, Kang SB, Kim HR
- KMID: 2532930
- Ann Surg Treat Res.
- 2022 Sep;103(3):176-182.
- doi: 10.4174/astr.2022.103.3.176
Purpose: The relationship between microsatellite instability (MSI) and tumor response after neoadjuvant chemoradiotherapy (nCRT) in rectal cancer remains unclear. The present study aimed to evaluate the association between MSI and... -
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- Impact of circumferential tumor location of mid to low rectal cancer on oncologic outcomes after preoperative chemoradiotherapy
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Park Hm, Song O, Lee J, Lee SY, Kim CH, Kim HR
- KMID: 2532363
- Ann Surg Treat Res.
- 2022 Aug;103(2):87-95.
- doi: 10.4174/astr.2022.103.2.87
Purpose: Some studies have suggested that circumferential tumor location (CTL) of rectal cancer may affect oncological outcomes. However, studies after preoperative chemoradiotherapy (CRT) are rare. This study aimed to evaluate... -
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- Pretreatment 18F‑FDG PET/CT‑Derived Parameters in Predicting Clinical Outcomes of Locally Advanced Upper Third Esophageal Squamous Cell Carcinoma After Definitive Chemoradiation Therapy
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Ha L, Chau N, Bieu B, Son M
- KMID: 2532368
- Nucl Med Mol Imaging.
- 2022 Aug;56(4):181-187.
- doi: 10.1007/s13139-022-00751-9
Purpose The aim of this study was to investigate whether standard uptake values (SUVs) of pretreatment 18F-FDG PET/CT were the surrogate parameters for predicting the outcomes in locally advanced esophageal... -
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- Predicting stage ypT0–1N0 for nonradical management in patients with middle or low rectal cancer who undergo neoadjuvant chemoradiotherapy: a retrospective cohort study
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Lee J, Yang IJ, Suh JW, Ahn Hm, Oh HK, Kim DW, Kim YH, Lee KH, Kang SB
- KMID: 2531145
- Ann Surg Treat Res.
- 2022 Jul;103(1):32-39.
- doi: 10.4174/astr.2022.103.1.32
Purpose: It is important to discover predictive factors that can identify rectal cancer patients who will respond well to neoadjuvant concurrent chemoradiotherapy (CCRT) to develop management strategies, preserve sphincter and... -
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- Analysis of thromboembolic events in head and neck cancer patients who underwent concurrent chemoradiotherapy with cisplatin
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Cho H, Choi JH, Kang SY, Lee HW, Choi YW, Kim TH, Ahn MS, Kim CH, Shin YS, Jang JY, Oh YT, Heo J, Sheen SS
- KMID: 2529662
- Korean J Intern Med.
- 2022 May;37(3):653-659.
- doi: 10.3904/kjim.2021.309
Background/Aims: The study investigated the incidence of thromboembolic events (TEE) in head and neck (H&N) cancer patients who received concurrent chemoradiotherapy (CCRT) with cisplatin, and analyzed the factors affecting TEE... -
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- Long-term survival after CCRT and HAIC followed by ALPPS for hepatocellular carcinoma with portal vein invasion: a case report
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Kim IJ, Yoo SH, Lee JI, Lee KS, Lee HW, Lim JH
- KMID: 2528301
- J Liver Cancer.
- 2022 Mar;22(1):84-90.
- doi: 10.17998/jlc.2022.03.07
There are various methods for treating advanced hepatocellular carcinoma with portal vein invasion, such as systemic chemotherapy, transarterial chemoembolization, transarterial radioembolization, and concurrent chemoradiotherapy. These methods have similar clinical efficacy... -
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- Impact of hematologic toxicities during concurrent chemoradiation for cervical cancer
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Shi F, Yoder AK, Mach C, Dalwadi S, Anderson ML, Hall TR, Ludwig MS
- KMID: 2527269
- Obstet Gynecol Sci.
- 2022 Mar;65(2):176-187.
- doi: 10.5468/ogs.21308
Objective To evaluate the prognostic significance of hematological toxicities during cervical cancer treatment. Methods Patients treated for cervical carcinoma with definitive chemoradiation were identified. Toxicities were assessed during weeks 1 to... -
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- Neoadjuvant chemotherapy with gemcitabine and cisplatin followed by selective bladder preservation chemoradiotherapy in muscle-invasive urothelial carcinoma of bladder
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Sung HH, Kim H, Kim R, Kim CK, Kwon GY, Park W, Song W, Jeong BC, Park SH
- KMID: 2526902
- Investig Clin Urol.
- 2022 Mar;63(2):168-174.
- doi: 10.4111/icu.20210407
Purpose: To assess the safety and efficacy of gemcitabine and cisplatin as neoadjuvant chemotherapy followed by selective bladder preservation chemoradiotherapy in muscle-invasive bladder cancer (MIBC). Materials and Methods: Patients with clinical... -
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- Polo-like kinase 4 as a potential predictive biomarker of chemoradioresistance in locally advanced rectal cancer
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Oh H, Kim SG, Bae SU, Byun SJ, Kim S, Lee JH, Hwang I, Kwon SY, Lee HW
- KMID: 2524228
- J Pathol Transl Med.
- 2022 Jan;56(1):40-47.
- doi: 10.4132/jptm.2021.10.07
Background: Polo-like kinase 4 (PLK4) is a serine/threonine protein kinase located in the centriole of the chromosome during the cell cycle. PLK4 overexpression has been described in a variety of... -
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- A novel gene signature associated with poor response to chemoradiotherapy in patients with locally advanced cervical cancer
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Kim KH, Chang JS, Byun HK, Kim YB
- KMID: 2536011
- J Gynecol Oncol.
- 2022 Jan;33(1):e7.
- doi: 10.3802/jgo.2022.33.e7
Objective We aimed to investigate the distinct transcriptional landscape in poor responders to concurrent chemoradiotherapy (CCRT) and to gain mechanistic insights into treatment resistance in cervical cancer. Methods RNA sequencing was performed in... -
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- Treatment of Superficial Esophageal Cancer: An Update
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Shin CM
- KMID: 2523592
- Korean J Gastroenterol.
- 2021 Dec;78(6):313-319.
- doi: 10.4166/kjg.2021.155
Superficial esophageal squamous cell carcinoma (SESCC) is an esophageal squamous cell carcinoma confined to the mucosa or superficial submucosa. Recent Korean Guidelines recommend an endoscopic resection as the first-line treatment... -
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- Lateral Pelvic Lymph Node Dissection After Neoadjuvant Chemoradiotherapy in Patients With Rectal Cancer: A Single-Center Experience and Literature Review
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Kim MC, Oh JH
- KMID: 2523366
- Ann Coloproctol.
- 2021 Dec;37(6):382-394.
- doi: 10.3393/ac.2021.00913.0130
Purpose: We aimed to evaluate the surgicopathological outcomes of lateral pelvic lymph node dissection (LPLD) and long-term oncological outcomes of selective LPLD after neoadjuvant chemoradiotherapy (nCRT) in patients with locally... -
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- Prognostic Factors and Treatment of Recurrence after Local Excision of Rectal Cancer
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Choi MS, Huh JW, Shin JK, Park YA, Cho YB, Kim HC, Yun SH, Lee WY
- KMID: 2522585
- Yonsei Med J.
- 2021 Dec;62(12):1107-1116.
- doi: 10.3349/ymj.2021.62.12.1107
Purpose: Indications for local excision in patients with rectal cancer remain controversial. We reviewed factors affecting survival rate and treatment effectiveness in cancer recurrence after local excision among patients with... -
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