J Korean Acad Rehabil Med.  2005 Oct;29(5):521-526.

Concurrence of Multiple Sclerosis and Brain Tumor: A case report

Affiliations
  • 1Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Korea. rmpyun@amc.seoul.kr
  • 2Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Korea.

Abstract

The concurrence of multiple sclerosis and primary intracranial neoplasm is uncommon. We reported a 15-year old girl known to have multiple sclerosis (MS), who later developed cerebral glioma. The tumor was documented on the brain magnetic resonance imaging during the work up for an apparent relapsing MS, and subsequently confirmed pathologically by stereotactic biopsy. Because no single clinical feature or diagnostic test was sufficient for the diagnosis of MS, a combination of both clinical and paraclinical studies should be included. If clinical and paraclincal studies are atypical, additional studies, such as brain biopsy, may help differential diagnosis of other MS mimicking diseases.

Keyword

Multiple sclerosis; Glioma

MeSH Terms

Adolescent
Biopsy
Brain Neoplasms*
Brain*
Diagnosis
Diagnosis, Differential
Diagnostic Tests, Routine
Female
Glioma
Humans
Magnetic Resonance Imaging
Multiple Sclerosis*
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