J Korean Acad Rehabil Med.  2003 Dec;27(6):868-874.

Tc-99m-ECD Brain Single Photon Emission Computed Tomography Findings in Cerebral Palsy: Comparison with Magnetic Resonance Imaging Findings

• Moon JL
• Lee BN
• Shin JE
• Song DH
• Kim EN

Abstract

OBJECTIVE
To investigate the correlation between magnetic resonance imaging (MRI) findings and single photon emission computed tomograpy (SPECT) in cerebral palsy (CP). METHOD: Fourty-one patients with CP underwent MRI and SPECT of the brain. The patients were divided into 5 groups. Group 1 was for the cases with normal findings on MRI and SPECT, group 2 for abnormal on MRI but normal on SPECT, group 3 for normal on MRI but abnormal on SPECT, group 4 for abnormal findings on both MRI and SPECT with same abnormal lesion and group 5 for abnormal findings on both MRI and SPECT but with different abnormal lesion. RESULTS: In group 2, periventricular leukomalacia (PVL) and cortical atrophy were shown on MRI. In group 3, decreased blood flow at cerebellum was shown on SPECT. In group 4, brain atrophy on MRI and the decreased blood flow at the same site on SPECT were shown. In group 5, 15 of 22 cases with PVL on MRI and decreased blood flow at cerebellum, thalamus, basal ganglia and the cortical areas were shown. CONCLUSION: Brain SPECT was more sensitive in the detection of cerebellum, thalamus and cortical blood flow abnormality. MRI was more sensitive in demonstration of white matter lesion.

Keyword

Cerebral palsy; Single photon emission computed tomography; Magnetic resonance image

MeSH Terms

Atrophy
Basal Ganglia
Brain*
Cerebellum
Cerebral Palsy*
Humans
Infant, Newborn
Leukomalacia, Periventricular
Magnetic Resonance Imaging*
Thalamus
Tomography, Emission-Computed, Single-Photon*