J Korean Pediatr Soc.  1994 Mar;37(3):397-404.

Tc-99m HMPAO Brain SPECT in a Patient with Neonatal Seizure and Right Cerebral Hemiatrophy

Abstract

Functional brain imaging is very important in the diagnosis and evaluation of the various neurologic disorders, In addition to electroencephalography (EEG) and positron emission tomography(PET), single photon emission computed tomography (SPECT)have increasingly gained importance in determination of disturbancesin regional brain functions. Both ictal and interictal Tc-99m hexamethy-propyleneamine oxime single photon emission computed tomography (TC-99m HMPAO SPECT)was done in a patient with the neonatal seizure and right cerebral hemiatrophy. The left parieto-occipital area revealed increased redioactivity during ictal stage and decreased radioactivities during interictal stage on Tc-99m HMPAO Brain SPECT. This brain ares was thought to be a epileptogenic focus. Ictal and interictal Tc-99m HMPAO brain SPECT could be a safe and sensitive diagnostic method in localization of epileptogenic foci.

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