J Korean Soc Pediatr Nephrol.  2007 Oct;11(2):255-263.

Outcomes of Chronic Peritoneal Dialysis by Various Modalities in Korean Children: A Single Center Study

• Lee SH
• Baek JS
• Lee HK
• Han KH
• Choi HJ
• Lee BH
• Cho HY
• Ha IS
• Cheong HI
• Choi Y

Abstract

PURPOSE: A single center cross sectional retrospective study was performed to compare the outcomes of different peritoneal dialysis(PD) modalities in Korean children.
METHODS
Among children dialyzed with PD between the year 2004 and 2007, 35 children had reliable data on PD adequacy after 3 to 15 months of dialysis. Subjects were grouped by their modalities; 17, 13 and 5 children were on continuous ambulatory PD(CAPD), continuous cyclic PD(CCPD) and nightly intermittent PD(NIPD), respectively. Body weight and height, number of patients taking anti-hypertensives and laboratory data including biochemical and hemoglobin levels were compared. Dialysis adequacy including weekly Kt/Vurea, creatinine clearance (Ccr) and daily water removal were also compared. Patients were sub-grouped by their peritoneal permeability characteristics.
RESULTS
The percentage of patients taking anti-hypertensives, monthly change in Z-scores of body weight and height and laboratory data did not differ among the groups. Patients on CAPD and CCPD showed similar dialysis adequacies. Weekly dialytic Ccr was significantly lower in the NIPD group compared to the others. But total Ccr was not different when residual renal function was added. Weekly dialytic Ccr by CAPD was significantly higher than that of CCPD in low and low-average transporters.
CONCLUSION
We propose that modality can be selected flexibly according to the patients' preferences. And peritoneal permeability characteristics provide valuable information for adjusting PD prescriptions in ultrafiltration failure or in inadequate dialysis. Further study of other clinical performance measures should be performed to clarify the comparable outcomes in different PD modalities.

Keyword

Chronic peritoneal dialysis; Continuous ambulatory peritoneal dialysis; Automated peritoneal dialysis; Continuous cyclic peritoneal dialysis; Nightly intermittent peritoneal dialysis; Dialysis adequacy

MeSH Terms

Antihypertensive Agents
Body Weight
Child*
Creatinine
Dialysis
Humans
Peritoneal Dialysis*
Peritoneal Dialysis, Continuous Ambulatory
Permeability
Prescriptions
Retrospective Studies
Ultrafiltration
Water
Antihypertensive Agents
Creatinine
Water