Psychiatry Investig.
2011 Sep;8(3):269-271.
Duloxetine-Induced Liver Injury in Patients with Major Depressive Disorder
- Affiliations
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- 1Department of Psychiatry, Catholic University of Daegu School of Medicine, Daegu, Korea.
- 2Department of Neuropsychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. medipark@hanmail.net
- 3Department of Psychiatry, Korea University College of Medicine, Seoul, Korea.
- 4Department of Psychiatry, Maumtomaum Clinic, Yongin, Korea.
Abstract
- Duloxetine is a balanced serotonin-norepinephrine reuptake inhibitor. Duloxetine-induced liver injury in patients with preexisting liver disease or chronic alcohol use is known. However, we have found that duloxetine can also induce liver injury in cases without those risk factors. We recommend that clinicians should monitor liver function carefully following duloxetine treatment.
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