Korean J Urol.  2013 Jun;54(6):409-411.

Leiomyosarcoma, a Nonurothelial Bladder Tumor: A Rare Entity With Therapeutic Diversity

• Gupta DK
• Singh V
• Sinha RJ
• Kumar V
• Nagathan D
• Sankhwar S

Abstract

A 22-year-old young woman presented with dysuria and lower urinary tract symptoms that had persisted for 6 months. She was diagnosed with a tumor near the bladder neck. Transurethral resection was done under anaesthesia. The histopathological examination with immunohistochemical staining showed the tumor to be a low-grade leiomyosarcoma. Adjuvant chemoradiation was given, and the patient has been doing well for 12 months of follow-up. Nonurothelial tumors of the bladder are rare and consensus is lacking regarding their definitive treatment. Furthermore, little is known about the natural history and prognosis of this type of bladder sarcoma. We present a minimally invasive treatment for this relatively rare tumor in which bladder preservation was achieved with no evidence of local or distant recurrences during the follow-up to date.

Keyword

Hematuria; Leiomyosarcoma; Urinary bladder neoplasms

MeSH Terms

Consensus
Dysuria
Female
Follow-Up Studies
Hematuria
Humans
Leiomyosarcoma
Lower Urinary Tract Symptoms
Natural History
Neck
Prognosis
Recurrence
Sarcoma
Urinary Bladder
Urinary Bladder Neoplasms

Figure

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  FIG. 1 Contrast computed tomography scan of the pelvis showing the bladder mass near the bladder neck.

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  FIG. 2 Microphotograph showing elongated or spindle-shaped cells disposed in bundles or fascicles or an interlacing pattern (H&E, ×200).

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  FIG. 3 The immunohistochemical staining revealed the whole specimen to be strongly positive for smooth muscle actin and desmin (×400).

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