Pediatr Allergy Respir Dis.  2000 Sep;10(3):242-247.

A Case of Bronchial Obstruction Caused by Charcot-Leyden Crystals

Affiliations
  • 1Department of Pediatics, College of Medicine, Yonsei University, Korea.
  • 2Department of Pediatrics, College of Medicine, Pochon Cha University, KangNam Cha Hospital, Seoul, Korea.
  • 3Department of Pediatrics, College of Medicine, Inje University, Ilsan Back Hospital, Ilsan, Korea.

Abstract

Charcot-Leyden crystals are slender, hexagonal, bipyramidal crystals formed predominantly from eosinophil but also from basophil granules composed of a single protein of 17,400 daltons of lysophospholipase activity. It has been identified in a variety of body fluids and tissues in human tissues and secretions in association with eosinophilic inflammatory reactions, asthma, myeloid leukemias, and allergic, parasitic, and other diseases. In this report, we describe a child with bronchial obstruction and subsequent atelectasis caused by Charcot-Leyden crystals containing fibronous material who was treated with flexible bronchofiberscope to remove it.

Keyword

Charcot-Leyden crystals; Bronchial obstruction; Atelectasis

MeSH Terms

Asthma
Basophils
Body Fluids
Child
Eosinophils
Humans
Leukemia, Myeloid
Lysophospholipase
Pulmonary Atelectasis
Lysophospholipase
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