Korean J Nephrol.
2007 Sep;26(5):630-633.
A Case of IgA Nephropathy Associated with Leptospirosis
- Affiliations
-
- 1Department of Internal Medicine, The Armed Forces Yangju Hospital, Gyeonggi Province, Korea. danieljoseph@hanmail.net
- 2Department of Internal Medicine, School of Medicine, Catholic University of Daegu, Korea.
Abstract
- Leptospirosis is a spirochaetal infectious disease caused by Leptospira interrogans. Multiple organ involvement may be encountered in leptospirosis. Early renal involvement is very common and characterized by tubulo-interstitial nephritis and tubular dysfunction. Rarely, diffuse mesangial proliferative glomerulonephritis may be seen. Immunoglobulin A nephropathy (IgA nephropathy) is defined by the predominant deposition of IgA in the glomerular mesangium. The secondary IgA nephropathy is thought to be caused by hepatobiliary disease, mucosal disease, infection, malignancy, some hematologic disease and systemic autoimmune or hypersensitivity disease. However, there are few reports about IgA nephropathy associated with leptospirosis. We herein report a case of IgA nephropathy in 21-year- old leptospirosis patient.
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