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Concurrent Anti-glomerular Basement Membrane Nephritis and IgA Nephropathy

Suh KS, Choi SY, Bae GE, Choi DE, Yeo MK

Anti–glomerular basement membrane (GBM) nephritis is characterized by circulating anti-GBM antibodies and crescentic glomerulonephritis (GN) with deposition of IgG along the GBM. In a limited number of cases, glomerular immune...
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A Case of Immunoglobulin A Pemphigus: Intraepidermal Neutrophilic Dermatosis Type

Heo JH, Yoon HS, Lee SH, Yeom SD, Kim L, Kim SC, Byun JW, Shin J, Choi GS

  • KMID: 2465959
  • Korean J Dermatol.
  • 2019 Sep;57(8):492-495.
Immunoglobulin A (IgA) pemphigus is a rare variant of an autoimmune bullous disease with IgA antibodies. IgA pemphigus is divided into 2 major subtypes: the subcorneal pustular dermatosis (SPD) type...
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Plasma Macrophage Migration Inhibitory Factor and CCL3 as Potential Biomarkers for Distinguishing Patients with Nasopharyngeal Carcinoma from High-Risk Individuals Who Have Positive Epstein-Barr Virus Capsid Antigen-Specific IgA

Xue N, Lin JH, Xing S, Liu D, Li SB, Lai YZ, Wang XP, Mao MJ, Zhong Q, Zeng MS, Liu WL

PURPOSE: The purpose of this study was to identify novel plasma biomarkers for distinguishing nasopharyngeal carcinoma (NPC) patients from healthy individuals who have positive Epstein-Barr virus (EBV) viral capsid antigen...
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A Case of Nail Dystrophy with Selective Immunoglobulin A Deficiency

Lim Y, Lee J, Byun HJ, Park CS, Park JH, Lee JH, Lee DY

  • KMID: 2433645
  • Korean J Dermatol.
  • 2019 Jan;57(1):41-43.
No abstract available.
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Murine γδ T Cells Render B Cells Refractory to Commitment of IgA Isotype Switching

Han HJ, Jang YS, Seo GY, Park SG, Kang SG, Yoon SI, Ko HJ, Lee GS, Kim PH

γδ T cells are abundant in the gut mucosa and play an important role in adaptive immunity as well as innate immunity. Although γδ T cells are supposed to be...
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IgA nephropathy in a patient with ankylosing spondylitis well controlled with etanercept

Lee DH, Kim GT, Hwang NK, Kim EH

Ankylosing spondylitis (AS) can involve the eye, gastrointestinal system, cardiopulmonary system, skin, kidneys, and spinal and peripheral joints. It is rarely accompanied by immunoglobulin A (IgA) nephropathy. Although IgA is...
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Characterization of Specific IgA Response to Antigenic Determinants of Helicobacter pylori Urease Encoded by ureA and ureB in Children

Shin MK, Jun JS, Kwon SW, Lee DH, Ha JH, Park JS, Song DH, Jung MH, Kang HL, Baik SC, Park JS, Youn HS, Cho MJ, Seo JH, Lee WK

Helicobacter pylori (H. pylori), a causative agent of chronic gastritis and gastric cancer, has several virulent factors for own survival and progression toward gastric diseases in human stomach. Of those,...
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Staphylococcal infection-associated crescentic immunoglobulin A nephropathy

Jung JH, Song JH, Ahn SH

No abstract available.
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A Case of Polymyositis Associated with Immunoglobulin A Nephropathy

Oh YJ, Park ES, Jang M, Kang EW, Kie JH, Lee SW, Song JJ, Park YB, Lee CH, Park JS

Polymyositis (PM) is a chronic inflammatory disease that predominantly affects muscles. Systemic organ involvement, including the respiratory and gastrointestinal tracts, is frequently observed in PM, but renal involvement is rare....
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Efficacy and safety of adding mizoribine to standard treatment in patients with immunoglobulin A nephropathy: A randomized controlled trial

Hirai K, Ookawara S, Kitano T, Miyazawa H, Ito K, Ueda Y, Kaku Y, Hoshino T, Mori H, Yoshida I, Kubota K, Yamaji Y, Takeda T, Nakamura Y, Tabei K, Morishita

BACKGROUND: Mizoribine (MZR) is an immunosuppressive drug used in Japan for treating patients with lupus nephritis and nephrotic syndrome and has been also reportedly effective in patients with immunoglobulin A...
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Concurrent Linear Immunoglobulin A Dermatosis, Hashimoto Thyroiditis, and Immunoglobulin A Nephropathy in an Adult

Yang JY, Park I, Kim SK

No abstract available.
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A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy

Kim JC, Kim YK, Hyun HS, Park EJ, Kang HG, Ha IS, Cheong HI

Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction. However,...
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Relationship between serum IgA level and allergy/asthma

Kim WJ, Choi IS, Kim CS, Lee JH, Kang HW

BACKGROUND/AIMS: Mucosal immunoglobulin A (IgA) may prevent the entrance of allergens. This study examined the relationship between serum IgA levels (within the normal range) and sensitization to house dust mites...
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Beneficial effects of tonsillectomy plus steroid pulse therapy on inflammatory and tubular markers in patients with IgA nephropathy

Maruyama S, Gohda T, Suzuki Y, Suzuki H, Sonoda Y, Ichikawa S, Li Z, Murakoshi , Horikoshi , Tomino Y

BACKGROUND: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide. Tonsillectomy plus steroid pulse therapy has been able to induce clinical remission in early-stage IgAN. However, its...
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Diagnosis and treatment of patients with IgA nephropathy in Japan

Tomino Y

Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. Although CKD is not one specific disease, it is...
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A Patient with IgA Nephropathy: 5 Years after Complete Remission of Minimal Change Nephrotic Syndrome

Kim JW, Park JH, Kim DH, Kim HY, Kim SH, Park WD

A 37-year-old male patient was admitted with generalized edema as the main symptom. A blood test confirmed hypoalbuminemia and hyperlipidemia, and a urine test confirmed severe albuminuria. A renal biopsy...
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Plasma endocan level and prognosis of immunoglobulin A nephropathy

Lee YH, Kim JS, Kim SY, Kim YG, Moon JY, Jeong KH, Lee TW, Ihm CG, Lee SH

BACKGROUND: Endocan, previously called endothelial cell–specific molecule-1, is a soluble proteoglycan that is secreted from vascular endothelial cells. Elevated plasma endocan levels were shown to be associated with poor cardiovascular...
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Elevated serum immunoglobulin E level as a marker for progression of immunoglobulin A nephropathy

Lee JH, Lee SY, Kim JS, Kim DR, Jung SW, Jeong KH, Lee TW, Lee YH, Kim YG, Moon JY, Lee SH, Ihm CG

BACKGROUND: Immunoglobulin E (IgE) has traditionally been associated with anaphylaxis and atopic disease. Previous studies reported that serum IgE levels are elevated in nephrotic syndrome and suggested IgE levels as...
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False-Positive Radioactive Iodine Uptake Mimicking Miliary Lung Metastases in a Patient Affected by Papillary Thyroid Cancer and IgA Deficiency

Demidowich AP, Kundu A, Reynolds J, Celi FS

A 42-year-old female with immunoglobulin A deficiency and recurrent sinopulmonary infections underwent thyroidectomy for papillary thyroid cancer (PTC). Follow-up ¹²³I scintigraphy demonstrated diffuse pulmonary uptake, suggesting metastatic disease. However, subsequent...
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Cross-Reactivity of Porcine Immunoglobulin A Antibodies with Fecal Immunoglobulins of Wild Boar (Sus scrofa) and Other Animal Species

Seo SW, Yoo SJ, Sunwoo S, Hyun BH, Lyoo YS

Fecal samples obtained from wild boar habitats are useful for the surveillance of diseases in wild boar populations; however, it is difficult to determine the species of origin of feces...
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