Korean J Med.
2008 Apr;74(4):441-444.
A case of primary effusion lymphoma
- Affiliations
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- 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. swkim@amc.seoul.kr
- 2Department of Thoracic Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract
- A 78-year-old woman was referred to this hospital because of exertional dyspnea for 2 weeks. Although she was treated with anti-tuberculous medication under the assumption that she had tuberculous pleuritis, her dyspnea continued. Physical examination revealed diminished breath sounds over the left lung field. Chest radiography showed a large left pleural effusion. The pleural effusion revealed malignant cell dominant exudates with a high adenosine deaminase level. Serological tests were negative for HIV. Computed tomography scan of the chest and abdomen showed pleural effusion, but no mass or pathological lymph nodes were detected. The biopsy specimen of the pleura was diagnosed as malignant B cell lymphoma with plasmacytoid features, suggesting a possibility of primary effusion lymphoma. Polymerase chain reaction assay of tumor was positive for HHV-8 DNA. She underwent pleurodesis during Video-Assisted Thoracic Surgery, and her dyspnea subsequently improved.
MeSH Terms
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Abdomen
Adenosine Deaminase
Aged
Biopsy
DNA
Dyspnea
Exudates and Transudates
Female
Herpesvirus 8, Human
HIV
Humans
Lung
Lymph Nodes
Lymphoma, B-Cell
Lymphoma, Primary Effusion
Physical Examination
Pleura
Pleural Effusion
Pleurisy
Pleurodesis
Polymerase Chain Reaction
Serologic Tests
Thoracic Surgery, Video-Assisted
Thorax
Adenosine Deaminase
DNA
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