Korean J Gastrointest Endosc.  2010 Dec;41(6):350-354.

Synchronous Incidental Occurrence of Gastric Gastrointestinal Stromal Tumor and Colon Adenocarcinoma

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. jwchulkr@yahoo.co.kr
  • 2Department of Surgery, The Catholic University of Korea College of Medicine, Seoul, Korea.

Abstract

A few cases of gastrointestinal stromal tumor (GIST) synchronous cancers with other malignancies have been reported, such as gastric cancer, pancreatic cancer, renal cell carcinoma, colon cancer, and carcinoid tumor. However, little is known about their coincidence with other tumors with a different histogenesis. A 62-year-old man visited our hospital with generalized weakness and intermittent hematochezia. A colonoscopic examination showed an ulcerating mass in the ascending colon, and a biopsy specimen revealed adenocarcinoma. A lobulated submucosal mass in the gastric fundus was found incidentally during the preoperative staging procedures, including computed tomography (CT) and positron emission tomography-CT. The colon cancer and gastric tumor were removed simultaneously (laparoscopy assisted right hemicolectomy and total gastrectomy). Immunohistochemical studies on the gastric tumor surgical specimen showed that it was CD117 (+) and CD34 (+), and the final diagnosis was a GIST of the stomach. Herein, we report a case of the synchronous occurrence of colon adenocarcinoma and gastric GIST.

Keyword

Gastrointestinal stromal tumor; Colon adenocarcinoma; Synchronous cancer

MeSH Terms

Adenocarcinoma
Biopsy
Carcinoid Tumor
Carcinoma, Renal Cell
Colon
Colon, Ascending
Colonic Neoplasms
Electrons
Gastric Fundus
Gastrointestinal Hemorrhage
Gastrointestinal Stromal Tumors
Humans
Middle Aged
Pancreatic Neoplasms
Stomach
Stomach Neoplasms
Ulcer
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