Korean J Helicobacter Up Gastrointest Res.  2013 Sep;13(3):182-188. 10.7704/kjhugr.2013.13.3.182.

Synchronous, Orthotopic Occurrence of Early Gastric Cancer with Gastrointestinal Stromal Tumor that Mimicked Advanced Gastric Cancer

  • 1Division of Gastroenterology, Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea. khsmhj@gmail.com
  • 2Department of General Surgery, Daegu Fatima Hospital, Daegu, Korea.
  • 3Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.


In recent years, the synchronous occurrence of two adjacent but histologically distinct tumors arising in the same organ has been reported. The simultaneous development of gastric adenocarcinoma and gastrointestinal stromal tumor (GIST) is very uncommon. The question raised was whether such a coexistence is a simple incidental finding or whether the two neighboring tumors are caused by a same unknown carcinogenic agent. Many doctors may have an interest in this rare condition and we expect further studies will be done in order to determine if there is any association between the two different tumors. We report a unique case of a synchronous, orthotopic occurrence of an early gastric cancer with GIST in the same location that mimicked advanced gastric cancer.


Gastric adenocarcinoma; Gastrointestinal stromal tumors; Synchronous tumor
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