Korean J Dermatol.  1997 Feb;35(1):191-195.

A Case of Idiopathic CD4 + T Lymphocytopenia Associated with Kaposi's Sarcoma

• Lee HT
• Jang HS
• Kwon KS
• Chung TA

Abstract

Idiopathic CD4+ T lymphocytopenia (ICL) is a new disease entity characterized by depletion of helper T cells apparently without any evidence of HIV infection. We report a case of ICL associated with Kaposis sarcoma (KS) and pneumocystis carinii pneumonia (PCP) in a 34-year old woman. She developed violaceous, protruding masses on scalp, back, both extremities, palms, soles, left. first toe and peritonsillar region for 2 months. These lesions were confirmed as KS by histopathologic findings. Chest X-ray and HRCT findings represented PCP and KS. Absolute deficiency of CD4+ T cell was detected in the count of T cell subsets. Serologic tests for HIV-1, 2 and HTLV I, -II were negative. And she was absent any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells. By CDC criteria, a diagnosis of ICL was made. Because of aggravation of PCP and lung involuement of KS, she died at 22nd day after admission.

Keyword

Idiopathic CD4+ T lymphocytopenia; Kaposis sarcoma

MeSH Terms

Adult
Centers for Disease Control and Prevention (U.S.)
Diagnosis
Extremities
Female
HIV Infections
HIV-1
Humans
Lung
Lymphopenia*
Pneumonia, Pneumocystis
Sarcoma, Kaposi*
Scalp
Serologic Tests
T-Lymphocyte Subsets
T-Lymphocytes
T-Lymphocytes, Helper-Inducer
T-Lymphocytopenia, Idiopathic CD4-Positive
Thorax
Toes