Korean J Dermatol.  2006 Jan;44(1):86-90.

A Case of Thin Acral Lentiginous Melanoma with Lymph Node Metastasis and Regression

Affiliations
  • 1Department of Dermatology, Maryknoll Hospital, Busan, Korea. yellowti@hanmail.net
  • 2Department of Surgery, Maryknoll Hospital, Busan, Korea.

Abstract

Contrary to general perception, thin acral lentiginous melanoma can metastasize. Sentinel lymph node metastases are found in a significantly greater proportion of patients with thin melanoma showing histological evidence of regression. In these cases, metastatic melanoma within lymph nodes may stimulate an immune response, resulting in regression of the primary lesion. However, a small number of thin acral lentiginous melanoma without regression also metastasize. We report a case of thin acral lentiginous melanoma with lymph node metastasis showing regression.

Keyword

Metastasis; Regression; Thin melanoma

MeSH Terms

Humans
Lymph Nodes*
Melanoma*
Neoplasm Metastasis*
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