Korean J Dermatol.
2006 Jan;44(1):83-85.
A Case of Radiation Recall Dermatitis after Hormonal Therapy of Letrozol (Femara(R))
- Affiliations
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- 1Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea. drseo@hanafos.com
- 2Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.
Abstract
- Radiation recall dermatitis gap (RRD) is the development of an inflammatory reaction throughout a previously irradiated area, precipitated by the administration of certain drugs. Usually chemotherapeutic agents have been associated with RRD, but other drugs reported include tamoxifen, interferon alfa-2b, simvastatin, and antituberculous drugs. We present a case of RRD after chemotherapy with letrozol (Femara(R)). Letrozol is a third generation aromatase inhibitor, which acts as an anti-estrogen agent. This is the first reported case of RRD triggered by letrozol.
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