Korean J Dermatol.
2007 May;45(5):453-457.
A Case of Desmoplastic Trichoepithelioma
- Affiliations
-
- 1Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea. kjahn@konkuk.ac.kr
- 2Department of Pathology, College of Medicine, Chung Ang University, Seoul, Korea.
Abstract
- Desmoplastic trichoepithelioma is a rare, benign, adnexal tumor of hair follicle origin and is most commonly found on the face of young females. Clinically it presents as a solitary, asymptomatic, firm and annular plaque with a raised border. The histopathological findings show narrow strands of basaloid tumor cells with variable nests in a trabecular pattern and horn cysts in the desmoplastic stroma. This closely resembles morphea type basal cell carcinoma and microcystic adnexal carcinoma. We herein report a case of desmoplastic trichoepithelioma on the cheek of a 22-year-old man, with discussion of the significance of the immunohistochemical stains in the differential diagnosis of similar skin tumors, using antibodies for CD10, CD34, CEA, CK14, CK7 and Bcl-2.
