Korean J Dermatol.  2012 Jun;50(6):569-573.

A Case of Primary Cutaneous Perivascular Epithelioid Cell Tumor

• Yang YJ
• Choi CW
• Lee GY
• Kim WS

Abstract

Perivascular epithelioid cell tumors (PEComas) are a rare, recently described group of mesenchymal tumors, which is composed of distinctive perivascular epithelioid cells. Primary cutaneous PEComas are composed of focally nested or trabecularly arranged groups of epithelioid cells with clear to eosinophilic cytoplasm and round to oval nuclei with obvious nucleoli. Here, we describe the case of a 27-year-old Korean man who was presented with a solitary, cutaneous nodule on his left popliteal fossa. Physical examination revealed a solitary, 1.2x1.0 cm-sized erythematous protruding nodule on his left popliteal fossa. Immunohistochemical evaluation showed that the epithelioid tumor cells were positive for HMB-45 and desmin. These clinical and histological findings were consistent with a diagnosis of primary cutaneous PEComa.

Keyword

PEComa; Perivascular epithelioid cells; Skin

MeSH Terms

Adult
Cytoplasm
Desmin
Eosinophils
Epithelioid Cells
Humans
Perivascular Epithelioid Cell Neoplasms
Physical Examination
Skin
Desmin