Korean J Anesthesiol.
2005 Sep;49(3):349-354. 10.4097/kjae.2005.49.3.349.
Correlations between the Modified Observer's Assessment of Alertness/Sedation Scale, Bispectral Index and Propofol Effect Site Concentrations in Sedated Elderly Patients under Regional Anesthesia
- Affiliations
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- 1Department of Anesthesiology and Pain Medicine, Medical School, Chonnam National University, Gwangju, Korea. anesman@jnu.ac.kr
- 2School of Density, Chonnam National University, Gwangju, Korea.
- KMID: 2299134
- DOI: http://doi.org/10.4097/kjae.2005.49.3.349
Abstract
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BACKGROUND: To maintain an adequate sedation level in elderly patients (over 65 years) under regional anesthesia, we evaluated the correlations between the modified observer's assessment of alertness/sedation (OAA/S) scale, bispectral index (BIS), propofol effect site concentrations.
METHODS
In elderly patients (over 65 years) scheduled for transurethral resection of a bladder tumor or prostate, we measured BISs and started propofol infusion using the target controlled infusion (TCI) method to sedate patients after regional anesthesia. OAA/S composite scores, measured BISs propofol effect site concentrations and vital signs were determined.
RESULTS
When the OAA/S composite score was 5, mean BIS was 97.2 +/- 1.1; when the OAA/S was 4, mean BIS was 84.3 +/- 4.6 and mean propofol effect site concentration was 0.8 +/- 0.3microgram/ml; when the OAA/S was 3, mean BIS was 78.4 +/- 4.3 and mean propofol effect site concentration was 1.2 +/- 0.3microgram/ml; and when the OAA/S was 2, mean BIS was 73.2 +/- 5.9 and mean propofol effect site concentration was 1.5 +/- 0.4microgram/ml. The OAA/S scale was found to be well correlated with BIS (Pearson's r = 0.973) and the propofol effect site concentration (Pearsons's r = -0.968). BIS was also well correlated with propofol effect site concentration (Pearson's r = -1.0).
CONCLUSIONS
BIS was found to be a good tool for monitoring sedation level in elderly patients under regional anesthesia with propofol sedation.
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