Korean J Urol.  2006 Feb;47(2):211-213. 10.4111/kju.2006.47.2.211.

Non-palpable and Asymptomatic Leydig Cell Tumor

• Kim JH
• Yang HJ
• Yoon JH
• Choi MS
• Lee DH
• Moon KH
• Song YS
• Park YH

• KMID: 2294204
• DOI: http://doi.org/10.4111/kju.2006.47.2.211

Abstract

Leydig cell tumors are the most common non-germ cell tumors of the testis, and they account for 1-3% of all testicular tumors. They most commonly present as a testicular mass and/or with endocrine symptoms. This tumor is characterized by its endocrine manifestations, which are due to the tumor's capacity to secrete hormones. We report here on one case of a patient with Leydig cell tumor; the patient was without symptoms and the tumor was not detected on the physical examination.

Keyword

Leydig cell tumor; Testis

MeSH Terms

Humans
Leydig Cell Tumor*
Physical Examination
Testicular Neoplasms
Testis

Figure

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  Fig. 1 The ultrasonographic findings show a 0.8×0.8cm sized hypoechogenic well marginated lesion in the upper portion of the right testis, which is confined within the tunica albuginea.

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  Fig. 2 T2 weighted axial image of the pelvic magnetic resonance imaging (MRI) shows a 1×1cm sized mass with low signal intensity, which is well marginated and has no infiltration beyond the tunica albuginea.

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  Fig. 3 Microscopic finding shows that the tumor is large and made of polygonal cells with abundant granular eosinophilic cytoplasm and prominent nucleoli (H&E, ×400).

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  Fig. 4 Immunohistochemistry shows positive staining for α-inhibin (Inhibin, ×200).

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