Korean J Urol.
2004 Sep;45(9):954-957.
A Localized Sarcomatoid Carcinoma of a Urinary Bladder Diverticulum
- Affiliations
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- 1Departments of Urology, Chonnam National University Medical School, Gwangju, Korea. sydad@hanmail.net
- 2Departments of Pathology, Chonnam National University Medical School, Gwangju, Korea.
Abstract
- A sarcomatoid carcinoma is an extremely rare tumor found in the urinary bladder, which accounts for 0.3% of all bladder malignancies. The development of malignancy within the bladder diverticulum often occurs, with the incidence varying between 2.9-4%. A sarcomatoid carcinoma of the urinary bladder is a highly malignant tumor containing both malignant mesenchymal and epithelial elements, which are demonstrated by immunohistochemical study. Recently, a case of a sarcomatoid carcinoma of the bladder diverticulum was experienced in a 41-year-old female. A partial cystectomy was performed under the impression of a bladder carcinoma in the diverticulum. Histopathologically, the tumor mass was composed of an urothelial carcinoma in the peripheral portion and sarcomatoid spindle cells in the central portion. Immunohistochemically, the epithelial components were stained with cytokeratin, but the sarcomatoid components were predominantly stained with vimentin, and focally with cytokeratin. The patient recovered without complications.
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