Utility and Safety of Midazolam Anesthesia during Cystoscopy

Lee, Sang Hun; Song, Yun Seob; Park, Young Ho

Abstract

PURPOSE
Although cystoscopy is useful for diagnosing urologic diseases, it is a painful procedure. Pain during cystoscopy can be reduced with the help of a midazolam induced anesthetic technique. However, the safety of anesthetic cystoscopy has not been established. This study investigated the value and safety of midazolam induced anesthetic cystoscopy. MATERIALS AND MTHODS: 50 male patients, who were examined with cystoscopy, were divided into two groups. Group I patients (n=25) received ketorolac 30mg. Group II patients (n=25) were treated with midazolam 3mg, which was increased to 5mg if necessary. All the group II patients were treated with flumazenil 0.2mg after anesthetic cystoscopy. There was no significant difference in age and weight. The mean midazolam dose was 3.72mg in group II. The blood pressure, pulse rate and respiratory rate were checked and the vital signs were monitored continuously by an oxymeter and electrocardiography. The sedation score, pain scale, recovery from sedation, and satisfaction were evaluated.
RESULTS
The pain scale in group II was significantly lower than that of group I. Although the blood pressure, pulse rate or respiratory rate changed slightly during cystoscopy, they were within the normal limit and there was no need for additional treatment. Recovery from anesthetic cystoscopy was good and satisfaction for the anesthetic cystoscopy was high.
CONCLUSIONS
The pain scale of the midazolam group was lower than that of control group and the patients' satisfaction is better than when using of conventional cystoscopy. Midazolam induced anesthetic cystoscopy is a useful and safe procedure.