Korean J Stroke.  2012 Dec;14(3):170-172.

Spontaneous Spinal Epidural Hematoma in a Patient on Cilostazol

• Baek SH
• Lee HS
• Kang JH
• Shin J
• Lee H
• Kim I
• Yang SJ
• Kim JS
• Shin DI
• Lee SH
• Lee SS

Abstract

Cilostazol is a phosphodiesterase inhibitor that has been shown to have similar efficacy in stroke prevention but fewer hemorrhagic events compared with aspirin. We report a case of spontaneous spinal epidural hematoma (SSEH) in a 67-year-old woman who has been treated with cilostazol for cerebral infarction. The patient was presented with sudden neck pain and right hemiparesis. Thirteen days after the onset, she recovered completely. Even cilostazol, which is a relatively safer drug in terms of bleeding risk compared to other antiplatelet agents, may cause SSEH. Therefore, physicians should keep in mind rare, but potentially fatal, bleeding complications such as SSEH when prescribing antiplatelet agents.

Keyword

Spontaneous spinal epidural hematoma; Cilostazol; Antiplatelet agents

MeSH Terms

Aspirin
Cerebral Infarction
Female
Hematoma, Epidural, Spinal
Hemorrhage
Humans
Neck Pain
Paresis
Platelet Aggregation Inhibitors
Stroke
Tetrazoles
Aspirin
Platelet Aggregation Inhibitors
Tetrazoles