Korean J Psychopharmacol.
2012 Jan;23(1):36-39.
Treatment of Psychiatric Symptoms in a Patient with Neuroacanthocytosis: A Case Report
- Affiliations
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- 1Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. jjean@catholic.ac.kr
Abstract
- Neuroacanthocytosis is a rare hereditary disorder characterized by various neurological symptoms and the presence of abnormal red blood cell called acanthocytosis. Degeneration of striatum, which accounts for characteristic motor and psychiatric symptoms, mainly attributes to the pathology of neuroacanthocytosis. We experienced a case of chorea-acanthocytosis. He was a 50 year-old-man who presented with orofacial dyskinesia, dysarthria, uncontrolled lip biting, generalized choreic movements and sensorymotor polyneuropathy. He was also suffered from obsessive eating behavior, disinhibition, impulsivity and sleep disturbance. After antipsychotic medication, his psychiatric problems were improved. Clinicians must consider psychiatric managements of progressive neurological disorder for patients' quality of life and reducing their caregiver's burden.
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