J Bone Metab.  2013 May;20(1):1-10. 10.11005/jbm.2013.20.1.1.

Sarcopenia: Definition, Epidemiology, and Pathophysiology

Affiliations
  • 1Department of Internal Medicine, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Korea.
  • 2Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea. medica7@gmail.com

Abstract

The epidemiological trends that characterize our generation are the aging of the population. Aging results in a progressive loss of muscle mass and strength called sarcopenia, which is Greek for 'poverty of flesh'. Sarcopenia could lead to functional impairment, physical disability, and even mortality. Today, sarcopenia is a matter of immense public concern for aging prevention. Its prevalence continues to rise, probably as a result of increasing elderly populations all over the world. This paper addressed the definition and epidemiology of sarcopenia and its underlying pathophysiology. In addition, we summarized the abundant information available in the literature related to sarcopenia, together with results from Korean sarcopenic obesity study (KSOS) that we performed.

Keyword

Aging; Body composition; Muscle mass; Sarcopenia; Sarcopenic obesity

MeSH Terms

Aged
Aging
Body Composition
Humans
Muscles
Obesity
Prevalence
Sarcopenia
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