J Asthma Allergy Clin Immunol.  2001 Dec;21(6):1211-1216.

A case of human toxocariasis with hypereosinophilic syndrome confirmed by serologic test

Affiliations
  • 1Department of Allergy and Clinical Immunology, Ajou University, School of Medicine, Suwon, Korea. hspark@madang.ajou.ac.kr
  • 2Department of Parasitology, Hallym University, College of Medicine, Chunchun, Korea.

Abstract

Human toxocariasis is defined as the infection of a human host by the larval stages of Toxocara canis, a common intestinal parasite of dogs. We experienced a patient with hypereosinophilic syndrome involving liver and stomach caused by human toxocariasis. The diagnosis of toxocariasis was confirmed by detecting serum specific IgE antibody to Toxocara excretory-secretory antigens (TES-Ag) by ELISA and IgG immunoblot analysis, with high sensitivity and specificity for the diagnosis of toxocariasis. Toxocariasis should be considered one of the causative diseases inducing hypereosinophilic syndrome in this country.

Keyword

Toxocariasis; eosinophilia; TES antigens; IgE antibodies; immunoblot

MeSH Terms

Animals
Diagnosis
Dogs
Enzyme-Linked Immunosorbent Assay
Eosinophilia
Humans*
Hypereosinophilic Syndrome*
Immunoglobulin E
Immunoglobulin G
Liver
Parasites
Sensitivity and Specificity
Serologic Tests*
Stomach
Toxocara
Toxocara canis
Toxocariasis*
Immunoglobulin E
Immunoglobulin G
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