J Asthma Allergy Clin Immunol.
2002 Jun;22(2):487-493.
A case of Churg-Strauss syndrome in association with leukotriene modifier therapy when oral corticosteroids were withdrawn in an asthmatic patient
- Affiliations
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- 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- 2Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
- 3Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
- 4Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Churg-Strauss syndrome is one of idiopathic, systemic necrotizing vasculitis characterized by a history of asthma or allergic rhinitis, eosinophilia of peripheral blood and variable symptoms of systemic vasculitis. There have been several recent case reports of Churg-Strauss syndrome in association with leukotriene modifier therapy when oral corticosteroids were withdrawn in asthmatic patients. We report a case of a 31-year-old man with steroid-dependent asthma who developed Churg-Strauss syndrome after 9 months of steroid withdrawal period, while he was receiving leukotriene modifier (Pranlukast).
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