Korean J Perinatol.  2015 Sep;26(3):260-264. 10.14734/kjp.2015.26.3.260.

Hemolytic Disease of the Newborn Caused by Anti-M in 2 Male Siblings

• Ahn SH
• Lee YK
• Ko SY
• Shin SM
• Cho DH

• KMID: 2281235
• DOI: http://doi.org/10.14734/kjp.2015.26.3.260

Abstract

Hemolytic disease of the newborn (HDN) caused by anti-M is rare and clinical manifestations are variable ranging from mild anemia and hyperbilirubinemia to hydrops fetalis and intrauterine fetal death. There were few reports of HDN caused by anti-M in Korea but no case in siblings. We experienced a case of 2 male siblings, both of whom had anti-M induced HDN and prolonged anemia persisted for over a month. We report this case with a brief review of literature. This report documents the first case of HDN caused by anti-M in siblings in Korea.

Keyword

Anti-M; Hemolytic disease of newborn; Anemia; Hyperbilirubinemia; Jaundice

MeSH Terms

Anemia
Erythroblastosis, Fetal
Fetal Death
Humans
Hydrops Fetalis
Hyperbilirubinemia
Infant, Newborn*
Jaundice
Korea
Male*
Siblings*

Figure

• 

  Fig. 1. Total bilirubin changes in case 1 and case 2.

• 

  Fig. 2. Hemoglobin changes in case 1 and case 2.

Reference

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