Korean J Otorhinolaryngol-Head Neck Surg.  2016 Jan;59(1):53-57. 10.3342/kjorl-hns.2016.59.1.53.

A Case of Maxillary Sinus Spindle Cell Sarcoma: Alert to Polyurethane Associated Malignancy

  • 1Department of Otorhinolaryngology-Head & Neck Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea. rhico@yonsei.ac.kr


There has been no literature that reports a case of sino-nasal malignancy associated with polyurethane implants. However, several previous in vitro and animal model studies revealed that polyurethane implants may cause malignancy in body tissue. In this report, we describe a case of maxillary sinus spindle cell sarcoma diagnosed in a 59-year-old man who had undergone polyurethane nasal packing in the nasal cavity following endoscopic sinus surgery two years ago. Complete removal of the packing material was not confirmed as the patient has not returned for postoperative care. Although there are no direct evidence of association between this spindle cell sarcoma case and polyurethane nasal packing, surgeons should be alert to the complete removal of polyurethane nasal packing after sino-nasal surgery.


Carcinogenicity; Polyurethane foam; Spindle cell sarcoma
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