Korean J Otorhinolaryngol-Head Neck Surg.  2022 Oct;65(10):634-638. 10.3342/kjorl-hns.2022.00752.

A Case of Carcinosarcoma Originating From Maxillary Sinus

• Lee TH
• Lee DB
• Lee SH
• Lee SH

• KMID: 2534454
• DOI: http://doi.org/10.3342/kjorl-hns.2022.00752

Abstract

Carcinosarcoma is a highly malignant tumor characterized by dual malignant histologic differentiation of epithelial and mesenchymal components, which rarely occurs in the maxillary sinus. We experienced a case of carcinosarcoma mixed with a keratinizing squamous cell carcinoma and an osteosarcoma arising from the right maxillary sinus recently. A 55-year-old male patient presented with right nasal obstruction and epistaxis. The initial punch biopsy revealed a high-grade sarcoma, favoring an osteosarcoma. After general evaluation, the patient was staged as cT4aN0M0. The patient was treated by right total maxillectomy, radiotherapy, and chemotherapy. We present with a review of the literature a case of a carcinosarcoma originating from the right maxillary sinus that had invaded into the orbital cavity and protruded into the nasal cavity.

Keyword

Carcinosarcoma; Maxillary sinus; Total maxillectomy