- An Alternative Dendritic Cell-Induced Murine Model of Asthma Exhibiting a Robust Th2/Th17-Skewed Response
-
Park SC, Kim H, Bak Y, Shim D, Kwon KW, Kim CH, Yoon JH, Shin SJ
- KMID: 2471235
- Allergy Asthma Immunol Res.
- 2020 May;12(3):537-555.
- doi: 10.4168/aair.2020.12.3.537
PURPOSE: Simple and reliable animal models of human diseases contribute to the understanding of disease pathogenesis as well as the development of therapeutic interventions. Although several murine models to mimic... -
- CITED
-
- Close
- SHARE
-
- Close
- Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas
-
Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ
- KMID: 2471734
- Endocrinol Metab.
- 2020 Mar;35(1):177-187.
- doi: 10.3803/EnM.2020.35.1.177
BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing... -
- CITED
-
- Close
- SHARE
-
- Close
- Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners
-
Kim SR, Park HJ, Lee KB, Kim HJ, Jeong JS, Cho SH, Lee YC
- KMID: 2468466
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):338-358.
- doi: 10.4168/aair.2020.12.2.338
PURPOSE: Phosphoinositide 3-kinase (PI3K)-δ-dependent Akt activation is known to play critical roles in various immune responses of white blood cells in which PI3K-δ isoform is mostly expressed in contrast to... -
- CITED
-
- Close
- SHARE
-
- Close
- Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model
-
Khalmuratova R, Lee M, Park JW, Shin HW
- KMID: 2468464
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):306-321.
- doi: 10.4168/aair.2020.12.2.306
PURPOSE: Osteitis refers to the development of new bone formation and remodeling of bone in chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal polyps (NPs), and recalcitrant... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of MicroRNA-34a in Anti-Apoptotic Effects of Granulocyte-Colony Stimulating Factor in Diabetic Cardiomyopathy
-
Park IH, Song YS, Joo HW, Shen GY, Seong JH, Shin NK, Cho YJ, Lee Y, Shin JH, Lim YH, Kim H, Kim KS
- KMID: 2470965
- Diabetes Metab J.
- 2020 Feb;44(1):173-185.
- doi: 10.4093/dmj.2018.0211
BACKGROUND: Recent studies have shown that microRNAs (miRNAs) are involved in the process of cardiomyocyte apoptosis. We have previously reported that granulocyte-colony stimulating factor (G-CSF) ameliorated diastolic dysfunction and attenuated... -
- CITED
-
- Close
- SHARE
-
- Close
- Cystic fibrosis lung disease: Current perspectives
-
Jung JA
- KMID: 2469112
- Allergy Asthma Respir Dis.
- 2020 Jan;8(1):3-8.
- doi: 10.4168/aard.2020.8.1.3
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). These mutations alter the synthesis, processing, function, or... -
- CITED
-
- Close
- SHARE
-
- Close
- Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system
-
Wei R, Lv J, Li X, Li Y, Xu Q, Jin J, Zhang Y, Liu Z
- KMID: 2469024
- J Vet Sci.
- 2020 Jan;21(1):e9.
- doi: 10.4142/jvs.2020.21.e9
Regenerative therapy holds great promise in the development of cures of some untreatable diseases such as cardiovascular diseases, and pluripotent stem cells (PSCs) including induced PSCs (iPSCs) are the most... -
- CITED
-
- Close
- SHARE
-
- Close
- The effect of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion
-
Hwang S, Chung CJ, Choi YJ, Kim T, Kim KH
- KMID: 2468640
- Korean J Orthod.
- 2020 Jan;50(1):42-51.
- doi: 10.4041/kjod.2020.50.1.42
OBJECTIVE: The objective of this study was to evaluate the effects of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion. METHODS: Sixty male Sprague–Dawley rats were... -
- CITED
-
- Close
- SHARE
-
- Close
- Animal model evaluation of a novel renal denervation system for future laparoscopic treatment of resistant hypertension
-
Song WH, Baik J, Yang S, Choi EK, Park SM, Jeong CW
- KMID: 2466799
- Investig Clin Urol.
- 2020 Jan;61(1):107-113.
- doi: 10.4111/icu.2020.61.1.107
PURPOSE: Although percutaneous catheter-based ablation of renal sympathetic nerve fibers has been used in the treatment of patients with resistant hypertension, a recent phase III study did not confirm its... -
- CITED
-
- Close
- SHARE
-
- Close
- History of Migraine and Volume of Brain Infarcts: The Italian Project on Stroke at Young Age (IPSYS)
-
Giuli VD, Besana M, Grassi M, Zedde M, Zini A, Lodigiani , Marcheselli S, Cavallini , Micieli G, Rasura M, DeLodovici ML, Tomelleri , Checcarelli N, Chiti A, Giorli E, Sette MD, Tancredi L, Toriello A, Braga M, Morotti A, Poli L, Caria F, Gamba M, Patella R, Spalloni A, Simone AM, Pascarella R, Beretta S, Fainardi E, Padovani A, Gasparotti R, Pezzini A, the Italian Project on Stroke in Young Adults (IPSYS) Investigators
- KMID: 2464649
- J Stroke.
- 2019 Sep;21(3):324-331.
- doi: 10.5853/jos.2019.00332
BACKGROUND AND PURPOSE: Migraine has been shown to increase cerebral excitability, promote rapid infarct expansion into tissue with perfusion deficits, and result in larger infarcts in animal models of focal... -
- CITED
-
- Close
- SHARE
-
- Close
- Modeling α-Synuclein Propagation with Preformed Fibril Injections
-
Chung HK, Ho HA, Pérez-Acuña D, Lee SJ
- KMID: 2464631
- J Mov Disord.
- 2019 Sep;12(3):139-151.
- doi: 10.14802/jmd.19046
The aggregation of α-synuclein (α-syn) has been implicated in the pathogenesis of many neurodegenerative disorders, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Postmortem... -
- CITED
-
- Close
- SHARE
-
- Close
- Early reduced bone formation following burn injury in rats is not inversely related to marrow adiposity
-
El Ayadi A, Helderman , Finnerty C, Herndon DN, Rosen CJ, Klein GL
- KMID: 2463599
- Osteoporos Sarcopenia.
- 2019 Sep;5(3):82-84.
- doi: 10.1016/j.afos.2019.08.001
OBJECTIVES: The objective of the study was to determine whether postburn reduction of bone formation occurred earlier than 2–3 weeks after burn injury and whether that reduction was inversely related... -
- CITED
-
- Close
- SHARE
-
- Close
- Ventilation accelerates lung injury in septic mice
-
Jung S, Kim S, Cho H, Jeong I, Park J, Jung DI, Yu D
- KMID: 2463592
- J Biomed Transl Res.
- 2019 Sep;20(3):58-64.
- doi: 10.12729/jbtr.2019.20.3.058
Sepsis is one of the systemic inflammatory responses, and it can cause acute respiratory distress syndrome (ARDS). Mechanical ventilation (MV) is one of the best treatments in patients with sepsis... -
- CITED
-
- Close
- SHARE
-
- Close
- SYM 2081 Exerts Neuroprotective Effect Modulating Anti-Apoptosis in the Hypoxic-Ischemic Brain Injury of Neonatal Rats
-
Park JK, Jang YY, Jeong JE, Lee EJ, Choi EJ, Chung HL, Kim WT
- KMID: 2460024
- Perinatology.
- 2019 Sep;30(3):117-125.
- doi: 10.14734/PN.2019.30.3.117
OBJECTIVE: SYM 2081 ((2S,4R)-4-methylglutamic acid), an agonist and functional antagonist of the kainite receptor, has shown a neuroprotective effect in neurodegenerative diseases in adults but little is known concerning perinatal... -
- CITED
-
- Close
- SHARE
-
- Close
- Epigenetics and Depression: An Update
-
Lin E, Tsai SJ
- KMID: 2459685
- Psychiatry Investig.
- 2019 Sep;16(9):654-661.
- doi: 10.30773/pi.2019.07.17.2
OBJECTIVE: Depression is associated with various environmental risk factors such as stress, childhood maltreatment experiences, and stressful life events. Current approaches to assess the pathophysiology of depression, such as epigenetics... -
- CITED
-
- Close
- SHARE
-
- Close
- Improvement in histology, enzymatic activity, and redox state of the liver following administration of Cinnamomum zeylanicum bark oil in rats with established hepatotoxicity
-
Niknezhad , Sayad-Fathi S, Karimzadeh A, Ghorbani-Anarkooli M, Yousefbeyk F, Nasiri E
- KMID: 2459546
- Anat Cell Biol.
- 2019 Sep;52(3):302-311.
- doi: 10.5115/acb.18.180
Formaldehyde (FA) is an environmentally-available pollutant. Since the liver acts as a detoxifier in the human body, it is the first and most affected organ in individuals exposed to higher-than-normal... -
- CITED
-
- Close
- SHARE
-
- Close
- Diabetes-related Amylin Dyshomeostasis: a Contributing Factor to Cerebrovascular Pathology and Dementia
-
Ly H, Despa F
- KMID: 2458379
- J Lipid Atheroscler.
- 2019 Sep;8(2):144-151.
- doi: 10.12997/jla.2019.8.2.144
Type 2 diabetes (T2D) increases the risk for cerebrovascular disease (CVD) and dementia. The underlying molecular mechanisms remain elusive, which hampers the development of treatment or/and effective prevention strategies. Recent... -
- CITED
-
- Close
- SHARE
-
- Close
- Shen-Kang protects against tacrolimus-induced renal injury
-
Zhang LY, Jin J, Luo K, Piao SG, Zheng HL, Jin JZ, Lim SW, Choi BS, Yang CW, Li C
- KMID: 2457031
- Korean J Intern Med.
- 2019 Sep;34(5):1078-1090.
- doi: 10.3904/kjim.2017.276
BACKGROUND/AIMS: Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a... -
- CITED
-
- Close
- SHARE
-
- Close
- Treatment with low-energy shock wave alleviates pain in an animal model of uroplakin 3A-induced autoimmune interstitial cystitis/painful bladder syndrome
-
Li H, Zhang Z, Peng J, Xin Z, Li M, Yang B, Fang D, Tang Y, Guo Y
- KMID: 2455963
- Investig Clin Urol.
- 2019 Sep;60(5):359-366.
- doi: 10.4111/icu.2019.60.5.359
PURPOSE: To investigate whether treatment with low-energy shock wave (LESW) alleviates pain and bladder dysfunction in a mouse model of uroplakin 3A (UPK3A)-induced interstitial cystitis/painful bladder syndrome (IC/PBS). MATERIALS AND METHODS:... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of gemigliptin on cardiac ischemia/reperfusion and spontaneous hypertensive rat models
-
Nam DH, Park J, Park SH, Kim KS, Baek EB
- KMID: 2455809
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):329-334.
- doi: 10.4196/kjpp.2019.23.5.329
Diabetes is associated with an increased risk of cardiovascular complications. Dipeptidyl peptidase-4 (DPP-IV) inhibitors are used clinically to reduce high blood glucose levels as an antidiabetic agent. However, the effect... -
- CITED
-
- Close
- SHARE
-
- Close
