Korean J Otorhinolaryngol-Head Neck Surg.  2014 May;57(5):320-324. 10.3342/kjorl-hns.2014.57.5.320.

Influences of Hashimoto's Thyroiditis as Prognostic Factor of Papillary Thyroid Carcinoma

• Park HJ
• Lee DK
• Seo JW
• Kang MK
• Park HS
• Kim RB
• Suh SH
• Park MK
• Kim DK
• Hong JC

• KMID: 2277900
• DOI: http://doi.org/10.3342/kjorl-hns.2014.57.5.320

Abstract

BACKGROUND AND OBJECTIVES
As a prognostic factor, the association of Hashimoto's thyroiditis (HT) with papillary thyroid carcinoma (PTC) is still controversial. The aim of this study is to compare clinicopathologic parameters between PTC alone and PTC with HT patients.
SUBJECTS AND METHOD
We reviewed the medical record retrospectively. 205 patients underwent thyroid surgery from January 2006 to December 2008. Among the 205 patients, 120 patients were included in this study. We compared various clinicopathologic parameters such as gender, tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, central lymph node metastasis, and lateral lymph node metastasis between PTC alone and PTC with HT patients.
RESULTS
18.3% of PTC patients were associated with HT. There were no significant differences in clinocopatholgic parameters such as gender, tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, central lymph node metastasis or lateral lymph node metastasis. Tumor recurrences were found in 6 out of 98 cases of PTC alone and in 3 out of 22 cases of PTC with HT. There was no significance between two groups (p=0.363).
CONCLUSION
Results indicate that HT may not be associated with clinicopathologic factors in PTC.

Keyword

Hashimoto's thyroiditis; Papillary thyroid carcinoma; Prognosis

MeSH Terms

Humans
Lymph Nodes
Medical Records
Neoplasm Metastasis
Prognosis
Recurrence
Retrospective Studies
Thyroid Gland*
Thyroid Neoplasms*
Thyroiditis*