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Radiomics Analysis of Gray-Scale Ultrasonographic Images of Papillary Thyroid Carcinoma > 1 cm: Potential Biomarker for the Prediction of Lymph Node Metastasis

Chung HJ, Han K, Lee E, Yoon JH, Park VY, Lee M, Cho E, Kwak JY

Purpose This study aimed to investigate radiomics analysis of ultrasonographic images to develop a potential biomarker for predicting lymph node metastasis in papillary thyroid carcinoma (PTC) patients. Materials and Methods This study included...
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Concurrent Primary Carcinoma and Metastatic Lesions of the Thyroid

Lee JS, Lee JS, Yun HJ, Lee YS, Chang HS

The thyroid gland is an infrequent site of metastases from other primary sites. Furthermore, concurrent primary carcinoma and metastatic disease of the thyroid gland is extremely rare. We report a case...
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Papillary Thyroid Carcinoma in a Separate Pyramidal Lobe Mimicking Thyroglossal Duct Cyst Carcinoma: A Case Report

Kang IK, Jung CK, Kim K, Park J, Kim JS, Bae J

There are sparse cases of carcinoma arising from the pyramidal lobe (PL). Thyroglossal duct cyst (TGDC), which is the most common anomaly concerning the thyroid gland, is typically where malignant...
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Risk Factors Associated With Persistent Disease, Recurrence and Evidence of Disease 5 Years After Treatment in Papillary Thyroid Cancers Smaller Than 2 cm With and Without Gross Extrathyroidal Extension

Min SK, Ko KP, Lee JH, Chung YS

Purpose: Papillary thyroid carcinomas (PTCs) are often characterized by recurrence, persistent disease, and evidence of disease 5 years after treatment. Such factors may be influenced by gross extrathyroidal extension (ETE),...
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Effect of Afatinib for Lung Cancer on Papillary Thyroid Carcinoma

Cho SH, Lee JS, Yun HJ, Lee YS, Chang HS

Papillary thyroid carcinoma is the most common type of thyroid cancer, for which surgery following preoperative staging and risk assessment is the standard treatment. Afatinib is an orally active irreversible...
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Papillary and medullary thyroid carcinomas coexisting in the same lobe, first suspected based on fine-needle aspiration cytology: a case report

Koh HH, Oh YL

Because different types of thyroid malignancies have distinct embryological origins, coexisting tumors are rarely observed. We describe a coexisting papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) first suspected...
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Thyroglobulin‑Based Risk Factor Repositioning for Determining Radioactive Iodine Activity in Patients with Papillary Thyroid Carcinoma: a Multicenter Retrospective Cohort Study

Jeon S, Kwon S, Lee S, Bae S

Purpose We aimed to investigate the impact of various factors including radioactive iodine (RAI) activity on the therapeutic response according to the range of serum thyroglobulin (Tg) in patients with...
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Correlation between myoferlin expression and lymph node metastasis in papillary thyroid carcinoma

Na JM, Kim DC, Song DH, An HJ, Koh HM, Lee JH, Lee JS, Yang JW, Kim MH

Background: Myoferlin is a multifunctional protein expressed in various normal and cancer cells, with novel oncogenic roles being newly discovered. Recently, correlations have been found between myoferlin expression and unfavorable...
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What is the difference between the tall cell variant and the classic type of papillary thyroid carcinoma on ultrasonography?

Kim H, Oh YL, Chung JH, Hahn SY, Park KW, Kim TH, Shin JH

Purpose: The prevalence of the tall cell variant of papillary thyroid carcinoma (TCVPTC), which has a poor prognosis, has increased as its definition has been modified. We sought to investigate...
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Using ultrasonographic features to predict the outcomes of patients with small papillary thyroid carcinomas: a retrospective study implementing the 2015 ATA patterns and ACR TI-RADS categories

Park HM, Lee J, Kwak JY, Park VY, Rho M, Lee M, Yoon JH

Background: The aim of this study was to evaluate whether risk stratification systems using ultrasonographic (US) features show associations with the outcomes of patients with small papillary thyroid carcinomas (PTCs). Methods:...
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Utility of sentinel lymph node biopsy in papillary thyroid microcarcinoma

Kim HY, Kim Di, Jung CS, Lee SJ, Im DW, Jung YJ, Yeom Ja, Choi JB

Purpose: There are many studies on sentinel lymph node (SLN) biopsy in thyroid carcinoma but SLN biopsy (SLNB) in papillary thyroid carcinoma (PTC) remains open to debate. Therefore in this...
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Collagenous Fibroma at the Surgical Site after Thyroidectomy for Papillary Thyroid Carcinoma

Yun JM, Chang S, So YK

Collagenous fibroma (CF) is a rare benign tumor that occurs at various anatomical sites including the head and neck. CFs are often omitted from differential diagnosis before surgery. We describe...
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Is Completion Thyroidectomy Necessary in Patients with Papillary Thyroid Carcinoma who Underwent Lobectomy?

Kang IK, Kim K, Bae JS, Kim JS

Background/Objectives: Although thyroid lobectomy recently is considered as sufficient for low-risk papillary thyroid carcinoma (PTC), completion thyroidectomy is required due to the insufficiency of the preoperative evaluation. The aim of...
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Kikuchi-Fujimoto Disease Masquerading as Bilateral Lymph Node Metastasis in a Patient With Papillary Thyroid Carcinoma: A Case Report and Literature Review

Jang DH, Lee WM, Yoon RG, Jung AR

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is common in young Asian women under the age of 30, and is usually characterized by fever, myalgia, fatigue, and cervical...
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Prediction of Gross Extrathyroidal Extension Using Preoperative Ultrasonography in Papillary Thyroid Cancer

Seo HS, Cheon YI, Kwon HK, Shin SC, Seo M, Cho Y, Sung ES, Lee JC, Kim BH, Kim IJ, Lee BJ

Background and Objectives The American Joint Committee on Cancer (AJCC) staging system 8th Edition has stated that gross extrathyroid extension (ETE) is more important than microscopic ETE, and that it...
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Expression of Estrogen and Progesterone Receptors in Papillary Thyroid Carcinoma in Korea

Ahn HY, Song RY, Ahn HS, Kim HS

Purpose The aim of this study was to examine the rate of expression of estrogen receptor α (ERα) and β1 (ERβ1), progesterone receptor (PR), and rate of overexpression of epidermal...
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Proto-oncogene Pokemon in thyroid cancer: a potential promoter of tumorigenesis in papillary thyroid carcinoma

Chang K, Do SI, Kim K, Chae SW, Do Ig, Lee HJ, Kim DH, Sohn JH

Background: Pokemon is an oncogenic transcription regulator that plays a critical role in cellular differentiation. Although it has been found to be overexpressed in several types of cancer involving different...
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Change of Therapeutic Response Classification According to Recombinant Human Thyrotropin‑Stimulated Thyroglobulin Measured at Different Time Points in Papillary Thyroid Carcinoma

Moon J, Jeon S, Park K, Yoo S, Kang S, Cho S, Kim J, Lee C, Song H, Min J, Bom H, Kwon S

Purpose: We investigated whether response classification after total thyroidectomy and radioactive iodine (RAI) therapy could be affected by serum levels of recombinant human thyrotropin (rhTSH)-stimulated thyroglobulin (Tg) measured at different...
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A Case of Intrathyroidal Spread of Papillary Thyroid Carcinoma

Lee JK, Cho YM, Lee JH, Woo JS, Cho JG

Papillary thyroid carcinoma (PTC) typically has a good prognosis, but it frequently metastasizes to the regional lymph nodes. Although survival impact of lymph node metastasis is not clear, complementary treatment...
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Branchial Cleft Cyst Mimicking Malignant Thyroid Neoplasm Concurrent with Medullary and Papillary Thyroid Carcinoma: a Case Report

Yi W, Kim BH, Lee BJ, Kim K

Branchial cleft cysts are the most common lateral neck mass, and usually have well-delineated cystic structures under ultrasonography. Ultrasonography and fine needle aspiration cytology is very helpful during preoperative diagnosis....
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