Korean J Otolaryngol-Head Neck Surg.  2005 Aug;48(8):1067-1070.

A Case of AIDS Related Non-Hodgkin's Lymphoma

Affiliations
  • 1Department of Otolaryngology, College of Medicine, Ewha Womans University, Seoul, Korea. sevent@ewha.ac.kr
  • 2Department of Pathology, College of Medicine, Ewha Womans University, Seoul, Korea.

Abstract

In an HIV-infected patient, cervical lymphadenopathy such as tubercuolosis, lymphoma, metastatic carcinoma must be differentiated from persistent generalized lymphadenopathy (PGL). Lymphoma is known as a late manifestation of HIV infection, generally occurring in patients with CD4+ T cell counts less than 200/microl. AIDS-related lymphomas were explained as variably associated with EBV infection, dysfunction of T cells, and HIV itself. The decision to perform a diagnostic open biopsy should be driven by a suspicion of malignancy or infection in the setting of a negative or inconclusive of FNA. Healthcare workers, especially those who deal with large numbers of HIV-infected patients, have a small but definite risk of becoming infected with HIV as a result of invasive procedures. Healthcare workers can minimize their risk of occupational HIV infection by following the guidelines discussed in this study.

Keyword

AIDS; Lymphoma

MeSH Terms

Biopsy
Cell Count
Delivery of Health Care
Epstein-Barr Virus Infections
HIV
HIV Infections
Humans
Lymphatic Diseases
Lymphoma
Lymphoma, AIDS-Related
Lymphoma, Non-Hodgkin*
T-Lymphocytes
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