Korean J Otolaryngol-Head Neck Surg.  2004 May;47(5):474-477.

A Case of NK/T Cell Lymphoma in Sinonasal Tract

Affiliations
  • 1Department of Otolaryngology, Pundang Jesaeng Hospital, Daejin Medical Center, Sungnam, Korea.

Abstract

Primary sinonasal NK/T cell lymphoma is relatively common in Asia than in Western countries, comprising up to 7% of all Non-Hodgkin's lymphoma with a marked preponderance demonstrating a NK/T-cell phenotype. Sinonasal NK/T cell lymphoma is typically associated with abundant crust on mucosal surface, widespread necrosis, and extensive inflammation. Sinonasal NK/T cell lymphoma is characterized by a progressive clinical course and poor prognosis, and histologically, it shows angioinvasion and necrosis. It is referred to by such terms as non-healing granuloma, lethal granuloma or midline granuloma. Treatment of NK/T cell lymphoma consists of radiotherapy, chemotherapy, or both. We experienced a case of sinonasal NK/T cell lymphoma in a 65 year old man who complained of periorbital swelling.

Keyword

Lymphoma; Non-hodgkin; Paranasal sinuses; Neoplasms

MeSH Terms

Aged
Asia
Drug Therapy
Granuloma
Humans
Inflammation
Lymphoma*
Lymphoma, Non-Hodgkin
Necrosis
Paranasal Sinuses
Phenotype
Prognosis
Radiotherapy
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