Chonnam Med J.
2002 Sep;38(3):288-292.
A Case of Portal Hypertensive Colopathy with Severe Colonic Edema
- Affiliations
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- 1Department of Internal Medicine, Namkwang Hospital, College of Medicine, Seonam University, Gwangju, Korea. liberte@medigate.net
- 2Department of PathologyNamkwang Hospital, College of Medicine, Seonam University, Gwangju, Korea.
- 3Department of Diagnostic Radiology, Namkwang Hospital, College of Medicine, Seonam University, Gwangju, Korea.
Abstract
- Portal hypertensive colopathy is a rare clinical entity caused by portal hypertension in patients with liver cirrhosis, which is manifested by various colonic mucosal and vascular lesions, such as edema, erythema, granularity, friability, atrophy, cherry-red spot, spider telangiectasia and angiodysplasia. Rarely, these lesions can cause life-threatening hemorrhage and other complications. However, the pathogenesis and clinical significance of these lesions have not yet been well documented. We have experienced a case of portal hypertensive colopathy in a 73-year-old man presenting symptoms of generalized weakness and melena. It was difficult to distinguish from infiltrative disease because of severe colonic mucosal thickening and edema throughout the entire colon. The diagnosis was established by histopathologic finding showing severe mucosal vascular congestion and hemorrhage. After treatment with oral propranolol, his clinical manifestations and colonic lesions were markedly improved.
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