Korean J Otolaryngol-Head Neck Surg.  1997 Feb;40(2):309-313.

A Case of Posterior Skull Base Adenocarcinoma Metastasized from The Prostate

• Park HM
• Rhee CK
• Cho CS

Abstract

Metastatic tumor of the skull base is uncommon. Diagnosis of the tumor is difficult without any associated evidence of another malignancy. It is distinguished from other benign or primary malignant tumor by rapid progression of symptoms, associated neurologic signs, and lytic or infiltrative lesion in imaging work-up study. Recently authors experienced one case of a posterior skull base adenocarcinoma metastasized from the prostate. Patient's initial complaints were hoarseness and aspiration due to vocal cord paralysis. He also complained of longstanding headache. On examination he had multiple cranial nerve paralyses of CN VII, VIII, X, XI, and XII. Radiologic study showed diffuse skull base lesion. Transmastoid biopsy revealed adenocarcinoma. With thorough examination a prostatic mass was found and proved to be the origin of the metastatic adenocarcinoma after transurethral biopsy. The patient was treated with "Flutamide".

Keyword

Skull base adenocarcinoma; Metastasis; Prostate

MeSH Terms

Adenocarcinoma*
Biopsy
Cranial Nerves
Diagnosis
Headache
Hoarseness
Humans
Neoplasm Metastasis
Neurologic Manifestations
Paralysis
Prostate*
Skull Base*
Skull*
Vocal Cord Paralysis