J Korean Neurosurg Soc.  2015 Mar;57(3):208-210. 10.3340/jkns.2015.57.3.208.

Sixth Cranial Nerve Palsy Caused by Gastric Adenocarcinoma Metastasis to the Clivus

Affiliations
  • 1Department of Radiology, Soonchunhyang University Hospital, Bucheon, Korea. aleerad@gmail.com
  • 2Department of Pathology, Soonchunhyang University Hospital, Bucheon, Korea.

Abstract

Tumors of the clivus and metastases to the clivus are very rare. Metastasis involving the clivus has previously been described in only two case reports. In skull metastasis, the breast and prostate are the most common primary foci, while metastasis from gastric carcinoma is extremely rare. A review of the English literature revealed only one published case of clivus metastases from gastric adenocarcinoma. There is no literature thoroughly explaining the differential diagnosis between chordoma and metastasis. Here we report a rare case of metastasis to the clivus from a gastric adenocarcinoma in a 42-year-old female patient with sudden blurry vision, presenting as bilateral cranial nerve VI palsy.

Keyword

Abducens nerve disease; Chordoma; Metastasis; Skull base

MeSH Terms

Abducens Nerve Diseases*
Adenocarcinoma*
Adult
Breast
Chordoma
Cranial Fossa, Posterior*
Diagnosis, Differential
Female
Humans
Neoplasm Metastasis*
Prostate
Skull
Skull Base
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