Korean J Obstet Gynecol.
2006 Apr;49(4):750-761.
New Trends of Preeclampsia
- Affiliations
-
- 1Department of Obstetrics and Gynecology, College of Medicine Keimyung University, Daegu, Korea. k1011@dsmc.or.kr
Abstract
- Preeclampsia is a leading cause of death and disability in mothers and infants. It's cause remains unknown. The only effective treatment is delivery. Preeclampsia is currently believed to be a 2-stage disease. The first stage is characterized by shallow cytotrophoblast invasion of maternal spiral arteriole, resulting in placental insufficiency. There are no maternal signs and symptoms during this stage. The hypoxic placenta release soluble factors into maternal circulation, which induce systemic endothelial dysfunction. This cause the second stage of the disease: the maternal syndrome. During this stage, the clinical signs of preeclampsia, are manifested. We review the evidence that an imbalance of circulating angiogenic factors, the prevention and treatment of preeclampsia including antioxidants for the prevention of preeclampsia, the expectant management and antihypertensive medications to treat mild and severe hypertension in women preeclampsia.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A study to compare maternal and perinatal outcome in early vs. late onset preeclampsia
- Anesthetic management for preeclampsia: Hemodynamic monitoring and volume therapy
- Preeclampsia and Innate Immunity
- Point Mutations in a Mitochondrial Transfer RiboNucleic Acid Gene in South Korean Women with Preeclampsia
- Study on the Hematologic and Blood Chemical Tests in Preelcampsia
