Korean J Obstet Gynecol.  2004 Oct;47(10):1987-1990.

A case of prenatally detected bilateral multicystic dysplastic kidney with chromosomal abnormality

• Yang HJ
• Kim HY
• Chung MJ
• Lee JH
• Jeong YJ
• Jin SJ
• Kim JD

Abstract

Multicystic dysplastic kidney (MCDK) is one of the most common causes of an abdominal mass in infants and it is the cystic anomaly most frequently identified antenatally by prenatal ultrasonography. The incidence of bilateral MCDK incidence is 1 in 5,000-10,000 births, but the prognosis is very poor due to association with other anomalies as well as chromosomal abnormalities. Recently, we performed prenatal diagnosis on a 26-year-old primigravida after a detection of oligohydramnios with bilateral MCDK on fetal ultrasonographic examination at 24 weeks gestation. Chromosomal analysis of the amniotic fluid cell cultures revealed a 46, XX, t(15;17)(p3;p12) karyotype. Bilateral MCDK was confirmed after autopsy, therefore we report this case with a review of brief literatures.

Keyword

Multicystic dysplastic kidney; Tranaslocation; Prenatal diagnosis

MeSH Terms

Adult
Amniotic Fluid
Autopsy
Cell Culture Techniques
Chromosome Aberrations*
Female
Humans
Incidence
Infant
Karyotype
Multicystic Dysplastic Kidney*
Oligohydramnios
Parturition
Pregnancy
Prenatal Diagnosis
Prognosis
Ultrasonography, Prenatal