Korean J Med.  2014 May;86(5):632-636.

A Case of Primary Autoimmune Myelofibrosis

Affiliations
  • 1Department of Internal Medicine, School of Medicine, CHA University, Seongnam, Korea. doh@cha.ac.kr
  • 2Department of Pathology, School of Medicine, CHA University, Seongnam, Korea.

Abstract

Primary autoimmune myelofibrosis, the development of which is not preceded by a well-defined autoimmune disease, has recently been defined as a distinct clinicopathologic syndrome. We report herein a case of a 68-year-old woman who was diagnosed with primary autoimmune myelofibrosis and present a review of the literature. The patient manifested peripheral pancytopenia, was positive for autoantibodies, and developed myelofibrosis with no preceding autoimmune or hematologic disorders. Her condition was dramatically improved after administration of prednisolone.

Keyword

Primary autoimmune myelofibrosis; Leukoerythroblastosis; Prednisolone
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