J Korean Rheum Assoc.  1998 Mar;5(1):108-115.

A Case of Systemic Lupus Erythematosus with Myelofibrosis

Abstract

A 42-year-old man presented with severe pancytopenia and uncontrolled epistaxis. The diagnosis of SLE was made and the pancytopenia was found to be due to myelofibrosis. The pulse therapy with methylprednisolone and maintenance therapy with prednisolone reversed both pancytopenia and myelofibrosis. Although myelofibrosis has been described in SLE, this coexistence must be very rare since there has been only 19 cases showing this combination. We report a case of SLE with myelofibrosis which was reversed by the treatment with glucocorticoid.

Keyword

Myelofibrosis; Pancytopenia; Glucocorticoid; Systemic Lupus Erythematosus
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