Korean J Med.  2015 Jun;88(6):701-705. 10.3904/kjm.2015.88.6.701.

Recurrence of Tuberculosis after Resuming a TNF-Inhibitor in a Patient with Crohn's Disease

Affiliations
  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. heathcliff6800@hanmail.net

Abstract

The use of tumor necrosis factor inhibitors (TNFi) increases a patient's risk of developing tuberculosis (TB). There is no consensus on whether restarting a TNFi after treating an active TB infection caused by previous TNFi exposure is safe. We report the first case of TB recurrence after recommencing a TNFi in a 37-year-old woman with a history of active TB infection caused by previous TNFi treatment.

Keyword

Tuberculosis; Tumor necrosis factor-alpha; Crohn disease; Recurrence

MeSH Terms

Adult
Consensus
Crohn Disease*
Female
Humans
Recurrence*
Tuberculosis*
Tumor Necrosis Factor-alpha
Tumor Necrosis Factor-alpha
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