Ann Dermatol.  2014 Feb;26(1):99-102. 10.5021/ad.2014.26.1.99.

Subdermal Coagulation Treatment of Axillary Bromhidrosis by 1,444 nm Nd:YAG Laser: A Comparison with Surgical Treatment

• Lee KG
• Kim SA
• Yi SM
• Kim JH
• Kim IH

• KMID: 2265705
• DOI: http://doi.org/10.5021/ad.2014.26.1.99

Abstract

Bromhidrosis is a disease presenting as malodor caused by interaction between the discharge of apocrine glands and bacteria. The main therapeutic modalities are applying topical agents, liposuction surgery, and elective surgery. Among these, elective surgery is reported to be most effective. However, the efficiency largely depends on surgical technique. Additionally, other side effects, such as hematoma and scarring, are occasionally reported. Currently, CO2 laser and 1,064 nm Nd:YAG laser therapy are used, but as the wavelength is not specific to apocrine glands, these laser therapies have certain limitations. Recently, a 1,444 nm wavelength Accusculpt(TM) laser (LutronicCorp., Seoul, Korea) has been developed which is now commonly used for facial fat plasty and laser liposuction therapy. The use of this laser for bromhidrosis therapy targeting apocrine sweat glands is currently being discussed. Still, no studies on practical clinical use and side effects of this 1,444 nm wavelength laser have been published. In this report, we treated one bromhidrosis patient with 1,444 nm wavelength Accusculpt(TM) laser therapy on one side while conventional surgery was performed on the other side using a modified Inaba's method. We compared the efficacy of this laser therapy to the surgical modality by measuring malodor severity and overall satisfaction by questionnaire. We also checked for other complications and recurrence for 12 months after the treatment. This patient was largely satisfied as it has a much shorter down time with the same therapeutic outcome. As subdermal coagulation treatment by 1,444 nm Nd:YAG laser may be less invasive but effective therapy, we would like to recommend this modality as a possible treatment option.

Keyword

Bromhidrosis; Nd:YAG; Subdermal coagulation; 1,444 nm

MeSH Terms

Apocrine Glands
Bacteria
Cicatrix
Hematoma
Humans
Laser Therapy
Lasers, Gas
Lipectomy
Recurrence
Seoul
Sweat Glands
Surveys and Questionnaires

Figure

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  Fig. 1 Left axilla of the patient (size: 10×5 cm, three parts).

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  Fig. 2 (A) Right axilla, 3 days following modified Inaba's operation. Ecchymosis was observed. (B) Left axilla, 10 days following laser operation; mild ecchymosis was observed. (C) Right axilla, 10 days following modified Inaba's operation; scar or crust was observed. (D) Left axilla, 10 days following laser operation; only mild crust without scarring was observed.

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  Fig. 3 Histologic examinations were done on the laser-irradiated area immediately post procedure and 6 months after the procedure (H&E, ×200). (A) Increased density of apocrine glands. Ablated adipocytes and apocrine glands are observed. (B) Decreased density of apocrine glands is observed.

Reference

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